This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
CD36 (human), (recombinant)
catalog :
ENZ-PRT170-0010
quantity :
10 µg
product information
Product ID :
ENZ-PRT170
Catalog Number :
ENZ-PRT170-0010
Product Name :
CD36 (human), (recombinant)
Product Type :
Protein
Size :
10 µg
Background :
CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL). It also may function as a cell adhesion molecule. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. It also binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. It also serves as a receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects. As a co-receptor for TLR4-TLR6 heterodimer, it promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42, it rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory response, leading to NF-κ-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MyD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL-1B secretion.
ALTnames :
SCARB3, GP3B, GP4, Platelet glycoprotein 4
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized from 0.22µm filtered solution in PBS, pH 7.4. Generally 5-8% mannitol or trehalose is added as a protectant before lyophilization.
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.