This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
ELISA/assay
product name :
Total PSA (human) ELISA kit
catalog :
ENZ-KIT146-0001
quantity :
96 wells
product information
Product ID :
ENZ-KIT146
Catalog Number :
ENZ-KIT146-0001
Product Name :
Total PSA (human) ELISA kit
Product Type :
Kit
Size :
96 wells
Product Description :
The Total PSA (human) ELISA kit is a colorimetric immunometric immunoassay kit with results in 2.5 hours.
SPECIES REACTIVITY :
Human
Background :
Prostate-specific antigen (PSA), also known as γ-seminoprotein or kallikrein-3 (KLK3), is a kallikrein-like protease produced by the epithelial cells in the prostate gland, the lining of the urethra, and the bulbourethral gland. It is a single-chain glycoprotein with a molecular weight of about 30-33kDa in human seminal plasma and it functions normally in the liquefaction of seminal coagulum. Under healthy condition, very little PSA is secreted in the blood. PSA exists in serum in multiple forms. The proteolytic activity of PSA in blood is inhibited by irreversible formation of complexes with proteinase inhibitors such as α1-antichymotrypsin (PSA-ACT complex), α2-macroglobulin (not detected by immunoassays) and other acute phase proteins. A small amount of PSA is not protein bound and is called 'free PSA”, which is also proteolytically inactive. Increases in glandular size and tissue damage caused by benign prostatic hypertrophy, prostatitis, or prostate cancer may increase circulating PSA levels. Monitoring the total PSA level in male blood has been used as an indicator for abnormal prostate function in the past decades. This assay provides an equal molar detection on different forms of PSA in human matrices, which improves the accuracy and sensitivity of the measurement on the total PSA levels.
ALTnames :
Prostate specific antigen, Kallikrein-3
Uses :
For the quantitative determination of Total PSA in human serum, plasma, urine and tissue culture media.
Application Summary :
ELISA, Colorimetric detection
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.