Cytokeratin 1/5/10/14 (human) monoclonal antibody (34βE12) | Enzo Life Sciences ENZ-C34903 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Cytokeratin 1/5/10/14 (human) monoclonal antibody (34βE12)

catalog :

ENZ-C34903

quantity :

0.5 ml

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

34?E12

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

Enzo Life Sciences product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:50; loading ...; fig 2a	Haffner M, Weier C, Xu M, Vaghasia A, GÃ¼rel B, GÃ¼mÃ¼ÅŸkaya B, et al. Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization. J Pathol. 2016;238:31-41 pubmed publisher
immunohistochemistry; human	Meunier R, Pareek G, Amin A. Metastasis of Malignant Melanoma to Urinary Bladder: A Case Report and Review of the Literature. Case Rep Pathol. 2015;2015:173870 pubmed publisher
	Lotan T, Gumuskaya B, Rahimi H, Hicks J, Iwata T, Robinson B, et al. Cytoplasmic PTEN protein loss distinguishes intraductal carcinoma of the prostate from high-grade prostatic intraepithelial neoplasia. Mod Pathol. 2013;26:587-603 pubmed publisher
	Uramoto H, Yamada S, Hanagiri T. Immunohistochemical staining with deltaNp63 is useful for distinguishing the squamous cell component of adenosquamous cell carcinoma of the lung. Anticancer Res. 2010;30:4717-20 pubmed
	Cameselle Teijeiro J, Ruiz Ponte C, Loidi L, Suárez Peñaranda J, Baltar J, Sobrinho Simoes M. Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma. Am J Clin Pathol. 2001;115:486-93 pubmed
	Nakayama H, Kimura A, Okumichi T, Miyazaki E, Kajihara H, Enzan H. Metaplastic shadow cells in rectal adenocarcinoma: report of a case with immunohistochemical study. Jpn J Clin Oncol. 1997;27:427-32 pubmed
	Bello D, Webber M, Kleinman H, Wartinger D, Rhim J. Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18. Carcinogenesis. 1997;18:1215-23 pubmed
	Gown A, Vogel A. Monoclonal antibodies to human intermediate filament proteins. II. Distribution of filament proteins in normal human tissues. Am J Pathol. 1984;114:309-21 pubmed
	Gown A, Vogel A. Monoclonal antibodies to intermediate filament proteins of human cells: unique and cross-reacting antibodies. J Cell Biol. 1982;95:414-24 pubmed
	Hedrick L, Epstein J. Use of keratin 903 as an adjunct in the diagnosis of prostate carcinoma. Am J Surg Pathol. 1989;13:389-96 pubmed
	Grignon D, Ro J, Ordonez N, Ayala A, Cleary K. Basal cell hyperplasia, adenoid basal cell tumor, and adenoid cystic carcinoma of the prostate gland: an immunohistochemical study. Hum Pathol. 1988;19:1425-33 pubmed

product information

Product ID :

ENZ-C34903

Catalog Number :

ENZ-C34903

Product Name :

Cytokeratin 1/5/10/14 (human) monoclonal antibody (34βE12)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

0.5 ml

list of Pubmed id :

26106499, 21115930, 11293895, 9438008, 9214605, 6320650, 6183272, 2469333, 2461340

Clone :

34βE12

Isotype :

IgG1

SPECIES REACTIVITY :

Human

Immunogen :

Keratin solubilized from human stratum corneum.

Specificity :

34βE12 is specific for "high molecular weight" cytokeratins 1, 5, 10 and 14, corresponding to molecular weights 68, 58, 56.5 and 50 kDa, respectively, which are characteristically found in "complex" epithelium. The antibody reacts with all squamous and ductal epithelium as well as carcinomas such as squamous cell carcinoma and adenocarcinoma of ductal origin (e.g., breast, pancreas) but does not react with sarcoma, melanoma or lymphoma. This antibody reacts with benign small-acinar lesions of the prostate and has been shown to be useful as an adjunct in the identification of prostate carcinoma.

Buffer :

Liquid. In PBS containing 0.1% sodium azide and 1% BSA.

Application Summary :

IHC (PS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage