This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
ApoE4 monoclonal antibody (4E4)
catalog :
ENZ-ABS295-0100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4E4

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunoprecipitation
product information
Product ID :
ENZ-ABS295
Catalog Number :
ENZ-ABS295-0100
Product Name :
ApoE4 monoclonal antibody (4E4)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
Clone :
4E4
Isotype :
IgG1κ
SPECIES REACTIVITY :
Human
Background :
Apolipoproteins are plasma lipoproteins that function as transporters of lipids and cholesterol in the circulatory system. Human ApoE is an apolipoprotein that has three isoforms: ApoE2, ApoE3, and ApoE4. The ApoE4 variant is the largest known genetic risk factor for late-onset Alzheimer's disease, and while the exact mechanism remains to be determined, it appears there may be an interaction with beta-amyloid. Alzheimer's disease is characterized by build-ups of aggregates of the peptide beta-amyloid. Apolipoprotein E enhances proteolytic break-down of this peptide, both within and between cells. The isoform ApoE4 is not as effective as the others at promoting these reactions, resulting in increased vulnerability to AD in individuals with that gene variation.
ALTnames :
Apolipoprotein E4
Immunogen :
Synthetic peptide corresponding to residues surrounding Arg110 of human ApoE4 protein.
Specificity :
Recognizes endogenous levels of total ApoE4 protein.
Buffer :
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide.
Application Summary :
ELISA, IP, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.