Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

ELISA/assay

CYTAG™ TotalCGH Labeling kit

ENZ-42674-0100

2 x 100 Reactions

ENZ-42674-0100

CYTAG™ TotalCGH Labeling kit

Kit

2 x 100 Reactions

Comparative analysis of chromosome 15. Upon scanning, the quality of the labeling in DNA samples was visually inspected to demonstrate detection of known deletion in the Prader-Willi DNA. This demonstrates the superior labeling obtained with the CGH labeling kit from Enzo Life Sciences when compared with a competitor’s kit.

SNP analysis of a segment of chromosome 2. DNA was labeled with the Enzo kit (left) or a competitor’s kit (right). DNA was hybridized to Agilent’s CGH+SNP microarray. The Enzo kit cleanly identifies the sequence at SNPs while quantification of the SNP analysis of DNA labeled with a competitor’s labeling system is not as clean.

Comparative genomic hybridization (aCGH) is a powerful diagnostic tool for detecting DNA copy number gains and losses associated with chromosome abnormalities. aCGH provides an understanding of genetic disorders, cancers and other genomic aberrations.   With optimized, proprietary reagents, Enzo's CYTAG™ CGH Labeling Kits produce high quality data using as little as 0.25µg of genomic DNA, without a need for pre-amplification. Bulk quantity kit, 2 x 1000 reactions, is available upon special request.

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