NGAL (human) monoclonal antibody (5G5) | Enzo Life Sciences BPD-HYB-211-01-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

NGAL (human) monoclonal antibody (5G5)

catalog :

BPD-HYB-211-01-1

quantity :

1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G5

The same clone is also sold as:

Abcam: ab23477
Invitrogen: HYB 211-01-02
Santa Cruz Biotechnology: sc-57517

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

citations: 10

Reference
Tong Z, Kunnumakkara A, Wang H, Matsuo Y, Diagaradjane P, Harikumar K, et al. Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer. Cancer Res. 2008;68:6100-8 pubmed publisher
Dent C, Ma Q, Dastrala S, Bennett M, Mitsnefes M, Barasch J, et al. Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care. 2007;11:R127 pubmed
Hirsch R, Dent C, Pfriem H, Allen J, Beekman R, Ma Q, et al. NGAL is an early predictive biomarker of contrast-induced nephropathy in children. Pediatr Nephrol. 2007;22:2089-95 pubmed
Zappitelli M, Washburn K, Arikan A, Loftis L, Ma Q, Devarajan P, et al. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care. 2007;11:R84 pubmed
Wagener G, Jan M, Kim M, Mori K, Barasch J, Sladen R, et al. Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery. Anesthesiology. 2006;105:485-91 pubmed
Brunner H, Mueller M, Rutherford C, Passo M, Witte D, Grom A, et al. Urinary neutrophil gelatinase-associated lipocalin as a biomarker of nephritis in childhood-onset systemic lupus erythematosus. Arthritis Rheum. 2006;54:2577-84 pubmed
Parikh C, Jani A, Mishra J, Ma Q, Kelly C, Barasch J, et al. Urine NGAL and IL-18 are predictive biomarkers for delayed graft function following kidney transplantation. Am J Transplant. 2006;6:1639-45 pubmed
Trachtman H, Christen E, Cnaan A, Patrick J, Mai V, Mishra J, et al. Urinary neutrophil gelatinase-associated lipocalcin in D+HUS: a novel marker of renal injury. Pediatr Nephrol. 2006;21:989-94 pubmed
Mishra J, Dent C, Tarabishi R, Mitsnefes M, Ma Q, Kelly C, et al. Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet. 2005;365:1231-8 pubmed
Hvidberg V, Jacobsen C, Strong R, Cowland J, Moestrup S, Borregaard N. The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake. FEBS Lett. 2005;579:773-7 pubmed

product information

Product ID :

BPD-HYB-211-01

Catalog Number :

BPD-HYB-211-01-1

Product Name :

NGAL (human) monoclonal antibody (5G5)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

1 mg

list of Pubmed id :

18676832, 18070344, 17874137, 17678545, 16931980, 16868980, 16827865, 16773412, 15811456, 15670845

Clone :

5G5

Isotype :

IgG1κ

SPECIES REACTIVITY :

Human

Background :

Neutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) belongs to the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, and occurs as 25-kDa glycosylated single protein chain monomers which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. The expression and release of NGAL from renal tubules is dramatically increased by ischemic or nephrotoxic injury.

ALTnames :

Neutrophil gelatinase-associated lipocalin, Lipocalin 2, Siderocalin, Oncogene 24p3

Immunogen :

Recombinant human NGAL in monomer and dimer forms.

Buffer :

Liquid. In 0.01M phosphate buffer, pH 7.4, containing 0.5M sodium chloride and 15mM sodium azide.

Uses :

Detects a band of ~25kDa by Western blot.

Application Summary :

ELISA, IHC, WB