This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
N-Arachidonoyl-serotonin
catalog :
BML-VR106-0050
quantity :
50 mg
citations: 4
Reference
Maione S, De Petrocellis L, de Novellis V, Moriello A, Petrosino S, Palazzo E, et al. Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors. Br J Pharmacol. 2007;150:766-81 pubmed
D Argenio G, Valenti M, Scaglione G, Cosenza V, Sorrentini I, Di Marzo V. Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation. FASEB J. 2006;20:568-70 pubmed
de Lago E, Petrosino S, Valenti M, Morera E, Ortega Gutierrez S, Fernandez Ruiz J, et al. Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels. Biochem Pharmacol. 2005;70:446-52 pubmed
Bisogno T, Melck D, De Petrocellis L, Bobrov MYu -, Gretskaya N, Bezuglov V, et al. Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase. Biochem Biophys Res Commun. 1998;248:515-22 pubmed
product information
Product ID :
BML-VR106
Catalog Number :
BML-VR106-0050
Product Name :
N-Arachidonoyl-serotonin
Product Type :
Biochemical
Size :
50 mg
list of Pubmed id :
17279090, 16403786, 15963472, 9703957
Product Description :
Unnatural fatty acid-neurotransmitter conjugate. Potent TRPV1 antagonist (IC50=40nM). Inhibits fatty acid amide hydrolase (FAAH) (IC50=5.6mM). Enhances levels of anandamide and 2-AG in vivo. Displays analgesic activity in both acute and chronic peripheral pain models but shows little efficacy in an inflammatory bowel disease model.
Purity :
≥98% (TLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.