N-Arachidonoyldopamine | Enzo Life Sciences BML-VR104-0025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

N-Arachidonoyldopamine

catalog :

BML-VR104-0025

quantity :

25 mg

citations: 9

Reference
Sancho R, de La Vega L, Macho A, Appendino G, Di Marzo V, Munoz E. Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine. J Immunol. 2005;175:3990-9 pubmed
De Petrocellis L, Chu C, Moriello A, Kellner J, Walker J, Di Marzo V. Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels. Br J Pharmacol. 2004;143:251-6 pubmed
Price T, Patwardhan A, Akopian A, Hargreaves K, Flores C. Modulation of trigeminal sensory neuron activity by the dual cannabinoid-vanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide. Br J Pharmacol. 2004;141:1118-30 pubmed
O Sullivan S, Kendall D, Randall M. Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA). Br J Pharmacol. 2004;141:803-12 pubmed
Sancho R, Macho A, de La Vega L, Calzado M, Fiebich B, Appendino G, et al. Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-kappa B, NFAT, and activator protein 1 signaling pathways. J Immunol. 2004;172:2341-51 pubmed
Toth A, Kedei N, Wang Y, Blumberg P. Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat. Life Sci. 2003;73:487-98 pubmed
Chu C, Huang S, De Petrocellis L, Bisogno T, Ewing S, Miller J, et al. N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J Biol Chem. 2003;278:13633-9 pubmed
Huang S, Bisogno T, Trevisani M, Al Hayani A, De Petrocellis L, Fezza F, et al. An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A. 2002;99:8400-5 pubmed
Bezuglov V, Bobrov M, Gretskaya N, Gonchar A, Zinchenko G, Melck D, et al. Synthesis and biological evaluation of novel amides of polyunsaturated fatty acids with dopamine. Bioorg Med Chem Lett. 2001;11:447-9 pubmed

product information

Product ID :

BML-VR104

Catalog Number :

BML-VR104-0025

Product Name :

N-Arachidonoyldopamine

Product Type :

Biochemical

Size :

25 mg

list of Pubmed id :

16148147, 16148147, 15289293, 15006899, 14769783, 14764703, 12759142, 12569099, 12060783, 11229744

Product Description :

Endogenous, specific ligand for the CB1 receptor (CB1: Ki=250nM; CB2: Ki=12µM) [1] and TRPV1 [2] (EC50=50nM) found in nervous tissues [3, 4]. Immunosuppressant inhibiting T cell proliferation and phosphorylation of the NF-κB p65 subunit [5]. Potent vasorelaxant [6] and inhibitor of HIV-1 [7].

ALTnames :

N-Arachidonoyl-3-hydroxytyramine, NADA, AA-DA

Purity :

≥98% (TLC)

Storage :

-20°C