N-Oleoyldopamine | Enzo Life Sciences BML-VR102-0025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

N-Oleoyldopamine

catalog :

BML-VR102-0025

quantity :

25 mg

citations: 5

Reference
Szolcsanyi J, Sandor Z, Petho G, Varga A, Bölcskei K, Almási R, et al. Direct evidence for activation and desensitization of the capsaicin receptor by N-oleoyldopamine on TRPV1-transfected cell, line in gene deleted mice and in the rat. Neurosci Lett. 2004;361:155-8 pubmed
Sancho R, Macho A, de La Vega L, Calzado M, Fiebich B, Appendino G, et al. Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-kappa B, NFAT, and activator protein 1 signaling pathways. J Immunol. 2004;172:2341-51 pubmed
Chu C, Huang S, De Petrocellis L, Bisogno T, Ewing S, Miller J, et al. N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J Biol Chem. 2003;278:13633-9 pubmed
Iwakami S, Shibuya M, Tseng C, Hanaoka F, Sankawa U. Inhibition of arachidonate 5-lipoxygenase by phenolic compounds. Chem Pharm Bull (Tokyo). 1986;34:3960-3 pubmed
Tseng C, Iwakami S, Mikajiri A, Shibuya M, Hanaoka F, Ebizuka Y, et al. Inhibition of in vitro prostaglandin and leukotriene biosyntheses by cinnamoyl-beta-phenethylamine and N-acyldopamine derivatives. Chem Pharm Bull (Tokyo). 1992;40:396-400 pubmed

product information

Product ID :

BML-VR102

Catalog Number :

BML-VR102-0025

Product Name :

N-Oleoyldopamine

Product Type :

Biochemical

Size :

25 mg

list of Pubmed id :

15135917, 14764703, 12569099, 3815617, 1606635

Product Description :

Endogenous TRPV1 agonist (Ki=36nM, EC50=36nM) with weak affinity for rat CB1 receptor (Ki=1.6µM). Potent inhibitor of 5-lipoxygenase (IC50=7.5nM) and of early and late events in TCR mediated T cell activation. Inhibits NF-κB dependent transcriptional activity without affecting either degradation of the cytoplasmic NF-κB inhibitory protein, IκBα, or DNA binding activity.

ALTnames :

OLDA, N-[2-(3,4-Dihydroxyphenyl)ethyl]-9Z-octadecenamide

Purity :

≥98% (TLC)

Storage :

-20°C