This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
NEDP1 (human), (recombinant) (His-tag)
catalog :
BML-UW9770-0100
quantity :
100 µg
product information
Product ID :
BML-UW9770
Catalog Number :
BML-UW9770-0100
Product Name :
NEDP1 (human), (recombinant) (His-tag)
Product Type :
Protein
Size :
100 µg
Background :
NEDP1, a human NEDD8-specific protease, is highly conserved throughout evolution and equivalent proteins are present in yeast, plants, insects, and mammals. NEDP1 appears to be specific for NEDD8 as neither ubiquitin nor SUMO bearing COOH- terminal extensions are utilized as substrates. Inhibition studies and mutagenesis indicate that NEDP1 is a cysteine protease with sequence similarities to SUMO-specific proteases and the class of viral proteases typified by the adenovirus protease. in vivo NEDP1 deconjugates NEDD8 from a wide variety of substrates including the cullin component of SCF-like complexes. Thus NEDP1 is likely to play an important role in ubiquitin-mediated proteolysis by controlling the activity of SCF complexes.
ALTnames :
NEDD8-specific protease 1, SENP8, Sentrin-specific protease 8, Deneddylase 1
Buffer :
Liquid. In 50mM TRIS-Cl, pH 7.7, containing 50% glycerol, 1mM DTT.
Storage :
-80°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.