Poly-SUMO-3 chains ([SUMO-3]2-7) | Enzo Life Sciences BML-UW9675-0025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Poly-SUMO-3 chains ([SUMO-3]2-7)

catalog :

BML-UW9675-0025

quantity :

25 µg

product information

Product ID :

BML-UW9675

Catalog Number :

BML-UW9675-0025

Product Name :

Poly-SUMO-3 chains ([SUMO-3]2-7)

Product Type :

Protein

Size :

25 µg

Background :

Small Ubiquitin-like Modifier (SUMO) is involved in diverse biological processes ranging from transcriptional regulation to defining sub-cellular localization. SUMO-2 and SUMO-3 each contain an acceptor lysine (K11) that allows the formation of polySUMO chains by canonical means. Under appropriate conditions, SUMO-1 may also form polySUMO chains at sites not comprising a recognised SUMOylation motif. A number of studies have implicated important biological functions for SUMO polymers including roles in chromosome segregation, recovery from checkpoint arrest, DNA damage response and meiosis. PolySUMO conjugates identified include HIF1α, PARP1, TOP2, PCNA and PML.

ALTnames :

Sentrin-2

Purity :

≥95% (SDS-PAGE)

Buffer :

Liquid. In 50mM TRIS, pH 7.5, containing 150mM sodium cloride and 1mM DTT.

Uses :

Suggested uses:. DeSUMOylating enzyme (SENP) substrates. Investigation of polySUMO-3 chain recognition by and interaction with SUMO/polySUMO binding proteins. PolySUMOylation studies.

Storage :

-20°C