Ubiquitin (human), (recombinant) | Enzo Life Sciences BML-UW0280-0001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Ubiquitin (human), (recombinant)

catalog :

BML-UW0280-0001

quantity :

1 mg

product information

Product ID :

BML-UW0280

Catalog Number :

BML-UW0280-0001

Product Name :

Ubiquitin (human), (recombinant)

Product Type :

Protein

Size :

1 mg

Background :

The covalent attachment of ubiquitin to proteins (ubiquitinylation) and their subsequent proteasomal degradation plays a fundamental role in the regulation of cellular function through biological events involving cell cycle, differentiation, immune responses, DNA repair, chromatin structure, and apoptosis. Ubiquitinylation is achieved through three enzymatic steps. In an ATP-dependent process, the ubiquitin activating enzyme (E1) catalyzes the formation of a reactive thioester bond with ubiquitin, followed by its subsequent transfer to the active site cysteine of a ubiquitin carrier protein (E2). The specificity of ubiquitin ligation arises from the subsequent association of the E2-ubiquitin thioester with a substrate specific ubiquitin-protein isopeptide ligase (E3), which facilitates the formation of the isopeptide linkage between ubiquitin and its target protein.

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized

Uses :

For use in ubiquitinylation studies.

Storage :

-20°C