Anisomycin | Enzo Life Sciences BML-ST102-0050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Anisomycin

catalog :

BML-ST102-0050

quantity :

50 mg

citations: 10

Reference
Mawji I, Simpson C, Gronda M, Williams M, Hurren R, Henderson C, et al. A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis. Cancer Res. 2007;67:8307-15 pubmed
Kukushkin A, Svetlikova S, Amanzholov R, Pospelov V. Anisomycin abrogates repression of protooncogene c-fos transcription in E1A + cHa-ras-transformed cells through activation of MEK/ERK kinase cascade. J Cell Biochem. 2008;103:1005-12 pubmed
Rudy J, Biedenkapp J, Moineau J, Bolding K. Anisomycin and the reconsolidation hypothesis. Learn Mem. 2006;13:1-3 pubmed
Vázquez Macías A, Ruíz Mendoza A, Fonseca Sánchez M, Briones Orta M, Macias Silva M. Downregulation of Ski and SnoN co-repressors by anisomycin. FEBS Lett. 2005;579:3701-6 pubmed
Okulski P, Hess G, Kaczmarek L. Anisomycin treatment paradigm affects duration of long-term potentiation in slices of the amygdala. Neuroscience. 2002;114:1-5 pubmed
Hazzalin C, Le Panse R, Cano E, Mahadevan L. Anisomycin selectively desensitizes signalling components involved in stress kinase activation and fos and jun induction. Mol Cell Biol. 1998;18:1844-54 pubmed
Cano E, Hazzalin C, Kardalinou E, Buckle R, Mahadevan L. Neither ERK nor JNK/SAPK MAP kinase subtypes are essential for histone H3/HMG-14 phosphorylation or c-fos and c-jun induction. J Cell Sci. 1995;108 ( Pt 11):3599-609 pubmed
Kochi S, Collier R. DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis. Exp Cell Res. 1993;208:296-302 pubmed
Kardalinou E, Zhelev N, Hazzalin C, Mahadevan L. Anisomycin and rapamycin define an area upstream of p70/85S6k containing a bifurcation to histone H3-HMG-like protein phosphorylation and c-fos-c-jun induction. Mol Cell Biol. 1994;14:1066-74 pubmed
Kyriakis J, Banerjee P, Nikolakaki E, Dai T, Rubie E, Ahmad M, et al. The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 1994;369:156-60 pubmed

product information

Product ID :

BML-ST102

Catalog Number :

BML-ST102-0050

Product Name :

Anisomycin

Product Type :

Biochemical

Size :

50 mg

list of Pubmed id :

17804746, 17647273, 16452648, 15967445, 12207948, 9528756, 8586671, 8359223, 8289787, 8177321

Product Description :

Antibiotic. Activates JNK/SAPKs, p38 and MAP kinases but not ERKs leading to the phosphorylation of S6, histone H3 and HMG-14 and the induction of the immediate-early genes c-fos and c-jun. Induces apoptosis in the human monoblastoid cell line. Used at 300 ng/ml. Inhibits peptidyl transferase at higher concentrations. Used in the eradication of bean mildew. Inhibits other pathogenic fungi in plants.

ALTnames :

2-(p-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate

Purity :

≥97% (TLC)

Storage :

-20°C