Cathepsin F (human), (recombinant) | Enzo Life Sciences BML-SE568-0005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Cathepsin F (human), (recombinant)

catalog :

BML-SE568-0005

quantity :

5 µg

citations: 1

Reference
Peters J, Rittger A, Weisner R, Knabbe J, Zunke F, Rothaug M, et al. Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease. Biochem Biophys Res Commun. 2015;457:334-40 pubmed publisher

product information

Product ID :

BML-SE568

Catalog Number :

BML-SE568-0005

Product Name :

Cathepsin F (human), (recombinant)

Product Type :

Protein

Size :

5 µg

list of Pubmed id :

25576872

Background :

Recombinant glycosylated procathepsin F cloned from human cDNA (NM_003793), expressed in insect cells, and purified as the active form of the enzyme. Cathepsin F, a member of the papain family of lysosomal cysteine proteases, acts upon proteins such as MHC Class II-associated invariant chain and ApoB-100. It is inhibited by the cysteine proteinase inhibitor E-64 (Prod. No. BML-EI105) and cystatin C (Prod. No. BML-SE479). It is a lysosomal protease expressed in numerous tissues, notably brain and macrophages. It functions in the immune system and is implicated in disease states such as atherosclerosis, cancer, and angiogenesis.

Purity :

≥80% (SDS-PAGE)

Buffer :

Liquid. In 20mM NaOAc, pH 5.0, containing 2.5mM EDTA, 250mM sodium chloride and 20mM L-cysteine.

Uses :

Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.

Storage :

-80°C