Cathepsin K (human), (recombinant) | Enzo Life Sciences BML-SE553-0010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Cathepsin K (human), (recombinant)

catalog :

BML-SE553-0010

quantity :

10 µg

citations: 3

Reference
Kyostio Moore S, Piraino S, Berthelette P, Moran N, Serriello J, Bendele A, et al. Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis. Arthritis Res Ther. 2015;17:5 pubmed publisher
Barry Z, Platt M. Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation. J Biol Chem. 2012;287:27723-30 pubmed publisher
Wilder C, Park K, Keegan P, Platt M. Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues. Arch Biochem Biophys. 2011;516:52-7 pubmed publisher

product information

Product ID :

BML-SE553

Catalog Number :

BML-SE553-0010

Product Name :

Cathepsin K (human), (recombinant)

Product Type :

Protein

Size :

10 µg

list of Pubmed id :

25592743, 22730330, 21982919

Background :

Cathepsin K, a member of the papain family of cysteine proteases, acts upon proteins such as collagen, AL amyloid, kinin, and elastin. It is a lysosomal protease expressed primarily in osteoclasts, but also in other cell types such as macrophages. It functions in bone remodeling and is implicated in disease states such as osteoporosis, atherosclerosis, arthritis, and pycnodysostosis.

ALTnames :

Cathepsin O, Cathepsin O2

Purity :

≥95% (SDS-PAGE)

Buffer :

Liquid. In 50mM sodium acetate, pH 5.5, containing 50mM sodium chloride, 0.5mM EDTA and 5mM DTT.

Storage :

-80°C