Neprilysin (human), (recombinant) (His-tag) | Enzo Life Sciences BML-SE532-0010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Neprilysin (human), (recombinant) (His-tag)

catalog :

BML-SE532-0010

quantity :

10 µg

citations: 1

Reference
Rogeberg M, Furlund C, Moe M, Fladby T. Identification of peptide products from enzymatic degradation of amyloid beta. Biochimie. 2014;105:216-20 pubmed publisher

product information

Product ID :

BML-SE532

Catalog Number :

BML-SE532-0010

Product Name :

Neprilysin (human), (recombinant) (His-tag)

Product Type :

Protein

Size :

10 µg

Product Description :

Neprilysin is a glycosylated zinc endopeptidase whose physiological targets include bradykinin, glucagon, GLP-1, and neuropeptides. Preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1.

Background :

Neprilysin is an integral plasma membrane (or secreted soluble) protease that has has a broad expression pattern, but is most abundant in the kidney. Due to its involvement in cancer, Alzheimer’s and Parkinson’s diseases, hypertension, diabetes, and pain, it is an important research target.

ALTnames :

NEP, Neutral endopeptidase 24.11, Enkephalinase, CALLA, Common acute lymphoblastic leukemia antigen, CD10

Purity :

≥95% (SDS-PAGE)

Buffer :

Liquid. In 50mM TRIS, pH 8.0. containing 300mM sodium chloride and 20% glycerol.

Uses :

Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.

Storage :

-80°C