This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
HDAC6 (human), (recombinant) (His-tag)
catalog :
BML-SE508-0050
quantity :
50 µg
citations: 5
Reference
Mahal K, Kahlen P, Biersack B, Schobert R. 4-(1-Ethyl-4-anisyl-imidazol-5-yl)-N-hydroxycinnamide - A new pleiotropic HDAC inhibitor targeting cancer cell signalling and cytoskeletal organisation. Exp Cell Res. 2015;336:263-75 pubmed publisher
Isaacs J, Antony L, Dalrymple S, Brennen W, Gerber S, Hammers H, et al. Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Res. 2013;73:1386-99 pubmed publisher
Walter W, Beránek V, Fischermeier E, Diez S. Tubulin acetylation alone does not affect kinesin-1 velocity and run length in vitro. PLoS ONE. 2012;7:e42218 pubmed publisher
Huang W, Chen C, Chao S, Yu C, Yang C, Guh J, et al. Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors. Eur J Med Chem. 2011;46:4042-9 pubmed publisher
Ishiguro K, Ando T, Maeda O, Watanabe O, Goto H. Cutting edge: tubulin ? functions as an adaptor in NFAT-importin ? interaction. J Immunol. 2011;186:2710-3 pubmed publisher
product information
Product ID :
BML-SE508
Catalog Number :
BML-SE508-0050
Product Name :
HDAC6 (human), (recombinant) (His-tag)
Product Type :
Protein
Size :
50 µg
list of Pubmed id :
26101158, 23149916, 22870307, 21712146, 21278340
Background :
HDAC6 is a class II HDAC, a group defined by its member’s homology to the yeast HDAC HDA1. It is unique among human HDACs in that it contains two full deacetylase domains. A tubulin deacetylase, HDAC6 may act to promote autophagic clearing of huntingtin aggregates and retard HIV1 infection, but also to promote invasive motility in tumor cells.
ALTnames :
Histone deacetylase 6
Buffer :
Liquid. In 50mM TRIS, pH 8.0, 138 mM NaCl and 10% glycerol.
Storage :
-80°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.