This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
p38 (human), (recombinant) (His-tag)
catalog :
BML-SE499-0020
quantity :
20 µg
product information
Product ID :
BML-SE499
Catalog Number :
BML-SE499-0020
Product Name :
p38 (human), (recombinant) (His-tag)
Product Type :
Protein
Size :
20 µg
Background :
p38 is a member of the MAP kinase family and is activated by environmental stresses and some pro-inflammatory cytokines. This kinase is known to phosphorylate ATF2, ELK1, MEF2A, MAX, CDC25B, p53, and also some downstream kinases, such as MK2, MK3, PRAK, MNK1/2, and MSK1.These substrates implicate p38 in stress related transcription and cell cycle regulation. Several p38 inhibitors are in clinical trials for the treatment of chronic obstructive pulmonary disease, psoriasis, and rheumatoid arthritis.
ALTnames :
MAPK14, MAP kinase 14
Purity :
≥90% (SDS-PAGE)
Buffer :
Liquid. In 20mM TRIS/HCl, pH 8.0, 200mM NaCl, 5mM DTT, 0.1 % Tween-20, 10% glycerol.
Uses :
Useful to study enzyme regulation and kinetics, phosphorylate target substrates, screen for inhibitors.
Storage :
-80°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.