PTEN (human), (recombinant) (His-tag) | Enzo Life Sciences BML-SE402-0010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

PTEN (human), (recombinant) (His-tag)

catalog :

BML-SE402-0010

quantity :

10 µg

citations: 1

Reference
Wolhuter K, Whitwell H, Switzer C, Burgoyne J, Timms J, Eaton P. Evidence against Stable Protein S-Nitrosylation as a Widespread Mechanism of Post-translational Regulation. Mol Cell. 2018;69:438-450.e5 pubmed publisher

product information

Product ID :

BML-SE402

Catalog Number :

BML-SE402-0010

Product Name :

PTEN (human), (recombinant) (His-tag)

Product Type :

Protein

Size :

10 µg

Background :

PTEN (phosphatase and tensin homologue deleted on chromosome 10, MMAC) is a lipid phosphatase which can also act as a tyrosine, serine and threonine protein phosphatase. It is specific for acidic substrates such as phosphatidylinositol(3,4,5)-trisphosphate, which is its main biological substrate that mediates growth factor-induced activation of intracellular signalling through the serine-threonine kinase Akt. The tumor suppressor gene, PTEN, also known as MMAC1 or TEP1, has been isolated from a locus on chromosome 1Oq23; this protein is deleted or mutated in a large number of tumors. Germline mutations of PTEN have been identified in Cowden disease, Lhermitte-Duclos disease, and Bannayan-Zonana syndrome.

ALTnames :

Phosphatase and tensin homolog deleted on chromosome 10

Purity :

≥80% (SDS-PAGE)

Buffer :

Liquid. In 50mM TRIS-HCl, pH 8.0, containing 150mM sodium chloride, 5mM DTT, 0.03% Brij 35, 0.1mM EDTA and 20% glycerol.

Uses :

Can be used to study regulation and kinetics of PTEN, screen for PTEN inhibitors or activators or as positive control for Western blots.

Storage :

-80°C