pCAF (human), (recombinant) | Enzo Life Sciences BML-SE271-0050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

pCAF (human), (recombinant)

catalog :

BML-SE271-0050

quantity :

50 µg

citations: 5

Reference
Yang X. The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. Nucleic Acids Res. 2004;32:959-76 pubmed
Kiernan R, Brès V, Ng R, Coudart M, El Messaoudi S, Sardet C, et al. Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65. J Biol Chem. 2003;278:2758-66 pubmed
Roth S, Denu J, Allis C. Histone acetyltransferases. Annu Rev Biochem. 2001;70:81-120 pubmed
Trievel R, Li F, Marmorstein R. Application of a fluorescent histone acetyltransferase assay to probe the substrate specificity of the human p300/CBP-associated factor. Anal Biochem. 2000;287:319-28 pubmed
Sakaguchi K, Herrera J, Saito S, Miki T, Bustin M, Vassilev A, et al. DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 1998;12:2831-41 pubmed

product information

Product ID :

BML-SE271

Catalog Number :

BML-SE271-0050

Product Name :

pCAF (human), (recombinant)

Product Type :

Protein

Size :

50 µg

list of Pubmed id :

14960713, 12419806, 11395403, 11112280, 9744860

Background :

pCAF isthe catalytic histone acetyltransferase (HAT) subunit of the transcriptional coactivator complex of the same name. In addition to the histones H3 and H4, pCAF has been shown to acetylate various other proteins, including the transcription factors p533 and p654.

ALTnames :

p300/CREB-binding protein associated factor, Histone acetyltransferase pCAF

Purity :

≥95% (SDS-PAGE)

Buffer :

Liquid. In 20mM sodium citrate, pH 6.0, containing 0.25M NaCl, 1mg/ml BSA and 10% glycerol.

Uses :

Useful for studying pCAF kinetics and regulation, screening for inhibitors or activators, and radiolabeling of histone proteins or peptides with, for example, [3H]-Acetyl CoA.

Storage :

-80°C