This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
MMP-2 (catalytic domain) (human), (recombinant)
catalog :
BML-SE237-0010
quantity :
10 µg
citations: 6
Reference
Edkins T, Alhadeff J, Kwok V, Kalensky C, Rock M, Vidmar T, et al. Development and validation of novel enzyme activity methods to assess inhibition of matrix metalloproteinases (MMPs) in human serum by antibodies against enzyme therapeutics. J Pharm Biomed Anal. 2012;70:408-14 pubmed publisher
Harney A, Sole L, Meade T. Kinetics and thermodynamics of irreversible inhibition of matrix metalloproteinase 2 by a Co(III) Schiff base complex. J Biol Inorg Chem. 2012;17:853-60 pubmed publisher
Jabaiah A, Daugherty P. Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines. Chem Biol. 2011;18:392-401 pubmed publisher
Ali M, Cho W, Hudson B, Kassiri Z, Granzier H, Schulz R. Titin is a target of matrix metalloproteinase-2: implications in myocardial ischemia/reperfusion injury. Circulation. 2010;122:2039-47 pubmed publisher
Dixon J, Gaillard W, Rivers W, Koval C, Stroud R, Mukherjee R, et al. Heterogeneity in MT1-MMP activity with ischemia-reperfusion and previous myocardial infarction: relation to regional myocardial function. Am J Physiol Heart Circ Physiol. 2010;299:H1947-58 pubmed publisher
Skarja G, Brown A, Ho R, May M, Sefton M. The effect of a hydroxamic acid-containing polymer on active matrix metalloproteinases. Biomaterials. 2009;30:1890-7 pubmed publisher
product information
Product ID :
BML-SE237
Catalog Number :
BML-SE237-0010
Product Name :
MMP-2 (catalytic domain) (human), (recombinant)
Product Type :
Protein
Size :
10 µg
list of Pubmed id :
22854133, 22729838, 21439484, 21041693, 20935147, 19147221
Product Description :
Represents a naturally occurring active form of MMP-2 which lacks the C-terminal hemopexin domain. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected.
ALTnames :
Matrix metalloproteinase 2, Gelatinase A, 72 kDa Type IV collagenase
Purity :
≥90% (SDS-PAGE)
Buffer :
Liquid. In 50mM TRIS-HCl, pH 7.5, containing 300mM NaCl, 5mM CaCl2, 20µM ZnCl2, 0.05% Brij-35 and 20% glycerol.
Uses :
Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.
Storage :
-80°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.