This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
MMP-1 (catalytic domain) (human), (recombinant)
catalog :
BML-SE180-0010
quantity :
10 µg
citations: 3
Reference
Edkins T, Alhadeff J, Kwok V, Kalensky C, Rock M, Vidmar T, et al. Development and validation of novel enzyme activity methods to assess inhibition of matrix metalloproteinases (MMPs) in human serum by antibodies against enzyme therapeutics. J Pharm Biomed Anal. 2012;70:408-14 pubmed publisher
Jabaiah A, Daugherty P. Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines. Chem Biol. 2011;18:392-401 pubmed publisher
Gooyit M, Lee M, Hesek D, Boggess B, Oliver A, Fridman R, et al. Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors. Chem Biol Drug Des. 2009;74:535-46 pubmed publisher
product information
Product ID :
BML-SE180
Catalog Number :
BML-SE180-0010
Product Name :
MMP-1 (catalytic domain) (human), (recombinant)
Product Type :
Protein
Size :
10 µg
list of Pubmed id :
22854133, 21439484, 19824893
Background :
In an SDS-PAGE gel, the enzyme runs as a doublet (<20 kDa). The higher band represents the polypeptide described above, while spontaneous cleavage of the tag results in the lower band. Both species possess identical enzymatic activities.
ALTnames :
Matrix metalloproteinase 1, Interstitial collagenase, Fibroblast collagenase
Purity :
≥95% (SDS-PAGE)
Buffer :
Liquid. In 50mM TRIS, pH 7.5, containing 5mM calcium chloride, 300mM sodium chloride, 20µM zinc chloride, 0.5% Brij-35, and 30% glycerol.
Uses :
Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.
Storage :
-80°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.