Caspase-3 (human), (recombinant) | Enzo Life Sciences BML-SE169-5000 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Caspase-3 (human), (recombinant)

catalog :

BML-SE169-5000

quantity :

5000 U

citations: 7

Reference
Huq N, Seers C, Toh E, Dashper S, Slakeski N, Zhang L, et al. Propeptide-mediated inhibition of cognate gingipain proteinases. PLoS ONE. 2013;8:e65447 pubmed publisher
Oxendine S, Cowden J, Hinton D, Padilla S. Vulnerable windows for developmental ethanol toxicity in the Japanese medaka fish (Oryzias latipes). Aquat Toxicol. 2006;80:396-404 pubmed
Wheaton K, Riabowol K. Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor. Mol Cell Biol. 2004;24:7298-311 pubmed
Neumar R, Xu Y, Gada H, Guttmann R, Siman R. Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis. J Biol Chem. 2003;278:14162-7 pubmed
Thornberry N, Rano T, Peterson E, Rasper D, Timkey T, Garcia Calvo M, et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J Biol Chem. 1997;272:17907-11 pubmed
Talanian R, Quinlan C, Trautz S, Hackett M, Mankovich J, Banach D, et al. Substrate specificities of caspase family proteases. J Biol Chem. 1997;272:9677-82 pubmed
Mittl P, Di Marco S, Krebs J, Bai X, Karanewsky D, Priestle J, et al. Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone. J Biol Chem. 1997;272:6539-47 pubmed

product information

Product ID :

BML-SE169

Catalog Number :

BML-SE169-5000

Product Name :

Caspase-3 (human), (recombinant)

Product Type :

Protein

Size :

5000 U

list of Pubmed id :

17125851, 15282327, 12576481, 9218414, 9092497, 9045680

Background :

The major effector caspase of apoptosis, caspase-3 is responsible for cleavage of multiple cellular targets.

ALTnames :

CPP32, Yama, Apopain

Purity :

≥95% (SDS-PAGE)

Buffer :

Liquid. In 50mM HEPES, pH 7.4, 100mM sodium chloride, 0.5% CHAPS, 1mM EDTA, 10% glycerol and 10mM dithiothreitol.

Uses :

Can be used to study enzyme regulation and kinetics, cleave target substrates and screen for inhibitors.

Storage :

-80°C