Caspase-1 (human), (recombinant) | Enzo Life Sciences BML-SE168-5000 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

Caspase-1 (human), (recombinant)

catalog :

BML-SE168-5000

quantity :

5000 U

citations: 8

Reference
Bartok E, Bauernfeind F, Khaminets M, Jakobs C, Monks B, Fitzgerald K, et al. iGLuc: a luciferase-based inflammasome and protease activity reporter. Nat Methods. 2013;10:147-154 pubmed publisher
LaRock C, Cookson B. The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing. Cell Host Microbe. 2012;12:799-805 pubmed publisher
Phenix B, Lum J, Nie Z, Sanchez Dardon J, Badley A. Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss. Blood. 2001;98:1078-85 pubmed
Dang L, Talanian R, Banach D, Hackett M, Gilmore J, Hays S, et al. Preparation of an autolysis-resistant interleukin-1 beta converting enzyme mutant. Biochemistry. 1996;35:14910-6 pubmed
Yuan J, Shaham S, Ledoux S, Ellis H, Horvitz H. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell. 1993;75:641-52 pubmed
Thornberry N. Interleukin-1 beta converting enzyme. Methods Enzymol. 1994;244:615-31 pubmed
Thornberry N, Bull H, Calaycay J, Chapman K, Howard A, Kostura M, et al. A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature. 1992;356:768-74 pubmed
Cerretti D, Kozlosky C, Mosley B, Nelson N, Van Ness K, Greenstreet T, et al. Molecular cloning of the interleukin-1 beta converting enzyme. Science. 1992;256:97-100 pubmed

product information

Product ID :

BML-SE168

Catalog Number :

BML-SE168-5000

Product Name :

Caspase-1 (human), (recombinant)

Product Type :

Protein

Size :

5000 U

list of Pubmed id :

23291722, 23245324, 11493454, 8942655, 8242740, 7845238, 1574116, 1373520

Background :

First of the caspases described, caspase-1 was subsequently found to be homologous to Ced-3, the C. elegans caspase essential for apoptosis.

ALTnames :

Interleukin 1β converting enzyme, IL-1β converting enzyme, ICE

Purity :

≥90% (SDS-PAGE)

Buffer :

Liquid. In 50mM HEPES, pH 7.4, containing 100mM sodium chloride, 0.5% CHAPS, 1mM EDTA, 10% glycerol and 10mM DTT.

Uses :

Useful tool to study enzyme regulation and kinetics, cleave target substrates, screen for inhibitors.

Storage :

-80°C