Castanospermine | Enzo Life Sciences BML-S107-0100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Castanospermine

catalog :

BML-S107-0100

quantity :

100 mg

citations: 10

Reference
Duellman T, Burnett J, Shin A, Yang J. LMAN1 (ERGIC-53) is a potential carrier protein for matrix metalloproteinase-9 glycoprotein secretion. Biochem Biophys Res Commun. 2015;464:685-91 pubmed publisher
Durrant C, Moore S. Perturbation of free oligosaccharide trafficking in endoplasmic reticulum glucosidase I-deficient and castanospermine-treated cells. Biochem J. 2002;365:239-47 pubmed
Ahmed S, Nash R, Bridges C, Taylor D, Kang M, Porter E, et al. Antiviral activity and metabolism of the castanospermine derivative MDL 28,574, in cells infected with herpes simplex virus type 2. Biochem Biophys Res Commun. 1995;208:267-73 pubmed
Bartlett M, Warren H, Cowden W, Parish C. Effects of the anti-inflammatory compounds castanospermine, mannose-6-phosphate and fucoidan on allograft rejection and elicited peritoneal exudates. Immunol Cell Biol. 1994;72:367-74 pubmed
Pili R, Chang J, Partis R, Mueller R, Chrest F, Passaniti A. The alpha-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis, and inhibits tumor growth. Cancer Res. 1995;55:2920-6 pubmed
Pan Y, Hori H, Saul R, Sanford B, Molyneux R, Elbein A. Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin. Biochemistry. 1983;22:3975-84 pubmed
Saul R, Molyneux R, Elbein A. Studies on the mechanism of castanospermine inhibition of alpha- and beta-glucosidases. Arch Biochem Biophys. 1984;230:668-75 pubmed
Schachter H. Glycoproteins: their structure, biosynthesis and possible clinical implications. Clin Biochem. 1984;17:3-14 pubmed
Ostrander G, Scribner N, Rohrschneider L. Inhibition of v-fms-induced tumor growth in nude mice by castanospermine. Cancer Res. 1988;48:1091-4 pubmed
Repp R, Tamura T, Boschek C, Wege H, Schwarz R, Niemann H. The effects of processing inhibitors of N-linked oligosaccharides on the intracellular migration of glycoprotein E2 of mouse hepatitis virus and the maturation of coronavirus particles. J Biol Chem. 1985;260:15873-9 pubmed

product information

Product ID :

BML-S107

Catalog Number :

BML-S107-0100

Product Name :

Castanospermine

Product Type :

Biochemical

Size :

100 mg

list of Pubmed id :

26150355, 11942856 , 7887939, 7835980, 7540952, 6615812, 6424575 , 6368044, 3124955, 2999142

Product Description :

Plant alkaloid. Potent inhibitor of α- and β-glucosidases. Exhibits antiviral properties. Inhibits thyroglobulin secretion. Antitumor activity. Inhibits protein glycosylation. Prevents angiogenesis.

Purity :

≥95% (TLC)

Storage :

+4°C