Proteasome 19S Rpn10/S5a subunit monoclonal antibody (S5a-18) | Enzo Life Sciences BML-PW9250-0025 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Proteasome 19S Rpn10/S5a subunit monoclonal antibody (S5a-18)

catalog :

BML-PW9250-0025

quantity :

25 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

S5a-18

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; loading ...; fig 4i	Sambri I, D Alessio R, Ezhova Y, Giuliano T, Sorrentino N, Cacace V, et al. Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases. EMBO Mol Med. 2017;9:112-132 pubmed publisher
western blot; human; fig 2	Golnik R, Lehmann A, Kloetzel P, Ebstein F. Major Histocompatibility Complex (MHC) Class I Processing of the NY-ESO-1 Antigen Is Regulated by Rpn10 and Rpn13 Proteins and Immunoproteasomes following Non-lysine Ubiquitination. J Biol Chem. 2016;291:8805-15 pubmed publisher
western blot; human; fig 2	Pitcher D, de Mattos Shipley K, Tzortzis K, Auner H, Karadimitris A, Kleijnen M. Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure. EBioMedicine. 2015;2:642-8 pubmed publisher
western blot; rat; 1:2000	Huang Q, Wang H, Perry S, Figueiredo Pereira M. Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons. J Biol Chem. 2013;288:12161-74 pubmed publisher
	Martinez Noel G, Luck K, Kühnle S, Desbuleux A, Szajner P, Galligan J, et al. Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes. J Mol Biol. 2018;430:1024-1050 pubmed publisher
	Sparks A, Dayal S, Das J, Robertson P, Menendez S, Saville M. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a. Oncogene. 2014;33:4685-96 pubmed publisher
	Hendil K, Kriegenburg F, Tanaka K, Murata S, Lauridsen A, Johnsen A, et al. The 20S proteasome as an assembly platform for the 19S regulatory complex. J Mol Biol. 2009;394:320-8 pubmed publisher

product information

Product ID :

BML-PW9250

Catalog Number :

BML-PW9250-0025

Product Name :

Proteasome 19S Rpn10/S5a subunit monoclonal antibody (S5a-18)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

25 µl

list of Pubmed id :

26288836, 24121268

Clone :

S5a-18

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Rat, Bovine

ALTnames :

26S proteasome non-ATPase regulatory subunit 4, Antisecretory factor 1, Multiubiquitin chain-binding protein

Immunogen :

Recombinant full-length human Rpn10 protein.

Specificity :

Recognizes the Rpn10/S5a subunit of the 19S regulator complex.

Buffer :

Liquid. In PBS containing 10mM sodium azide.

Application Summary :

IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage