product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Proteasome 20S β1 subunit monoclonal antibody (MCP421)
catalog :
BML-PW8140-0025
quantity :
25 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MCP421
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 4
Golnik R, Lehmann A, Kloetzel P, Ebstein F. Major Histocompatibility Complex (MHC) Class I Processing of the NY-ESO-1 Antigen Is Regulated by Rpn10 and Rpn13 Proteins and Immunoproteasomes following Non-lysine Ubiquitination. J Biol Chem. 2016;291:8805-15 pubmed publisher
  • western blot; human; fig 3
Bollinger L, Powell J, Houmard J, Witczak C, Brault J. Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin-proteasome and autophagic/lysosomal proteolytic flux. Obesity (Silver Spring). 2015;23:1185-93 pubmed publisher
  • western blot; human; 1:1000; fig  5
Balsas P, Galán Malo P, Marzo I, Naval J. Bortezomib resistance in a myeloma cell line is associated to PSM?5 overexpression and polyploidy. Leuk Res. 2012;36:212-8 pubmed publisher
Poli M, Ebstein F, Nicholas S, de Guzman M, Forbes L, Chinn I, et al. Heterozygous Truncating Variants in POMP Escape Nonsense-Mediated Decay and Cause a Unique Immune Dysregulatory Syndrome. Am J Hum Genet. 2018;102:1126-1142 pubmed publisher
Homma T, Kurahashi T, Lee J, Kang E, Fujii J. SOD1 deficiency decreases proteasomal function, leading to the accumulation of ubiquitinated proteins in erythrocytes. Arch Biochem Biophys. 2015;583:65-72 pubmed publisher
Hamouda M, Belhacene N, Puissant A, Colosetti P, Robert G, Jacquel A, et al. The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells. Oncotarget. 2014;5:6252-66 pubmed
Dechavanne V, Vilbois F, Glez L, Antonsson B. Purification and separation of the 20S immunoproteasome from the constitutive proteasome and identification of the subunits by LC-MS. Protein Expr Purif. 2013;87:100-10 pubmed publisher
product information
Product ID :
BML-PW8140
Catalog Number :
BML-PW8140-0025
Product Name :
Proteasome 20S β1 subunit monoclonal antibody (MCP421)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
25 µl
list of Pubmed id :
26264915, 26010327, 25051369, 23147206, 21978467
Clone :
MCP421
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Yeast, Rabbit
ALTnames :
Proteasome subunit β type-6, Macropain δ chain, Proteasome subunit Y
Immunogen :
Dinitrophenylated proteasomes.
Specificity :
Recognizes the β1 subunit of the 20S proteasome.
Buffer :
Liquid. In PBS containing 10mM sodium azide.
Application Summary :
IHC, WB
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.