This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Rolipram
catalog :
BML-PD175-0010
quantity :
10 mg
citations: 6
Reference
Wang Z, Zhang L, Liang Y, Zhang C, Xu Z, Zhang L, et al. Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin. Sci Rep. 2015;5:12012 pubmed publisher
Mullershausen F, Zécri F, Cetin C, Billich A, Guerini D, Seuwen K. Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. Nat Chem Biol. 2009;5:428-34 pubmed publisher
Underwood D, Kotzer C, Bochnowicz S, Osborn R, Luttmann M, Hay D, et al. Comparison of phosphodiesterase III, IV and dual III/IV inhibitors on bronchospasm and pulmonary eosinophil influx in guinea pigs. J Pharmacol Exp Ther. 1994;270:250-9 pubmed
Reeves M, Leigh B, England P. The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors. Biochem J. 1987;241:535-41 pubmed
Schneider H, Schmiechen R, Brezinski M, Seidler J. Stereospecific binding of the antidepressant rolipram to brain protein structures. Eur J Pharmacol. 1986;127:105-15 pubmed
Moore J, Combs D, Tobia A. Bemoradan--a novel inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue. Biochem Pharmacol. 1991;42:679-83 pubmed
product information
Product ID :
BML-PD175
Catalog Number :
BML-PD175-0010
Product Name :
Rolipram
Product Type :
Biochemical
Size :
10 mg
list of Pubmed id :
26153625, 19430484, 8035322, 3036066, 3019721, 1650219
Product Description :
Selective, cell permeable inhibitor of cAMP-specific phosphodiesterase (PDE IV, IC50=1 µM). A rolipram insensitive PDE IV subtype has been described.
ALTnames :
(±)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
Purity :
≥98% (TLC)
Storage :
Ambient
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.