NF-κB SN50M cell permeable control peptide | Enzo Life Sciences BML-P601-0500 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

NF-κB SN50M cell permeable control peptide

catalog :

BML-P601-0500

quantity :

0.5 mg

citations: 4

Reference
Tomasello D, Gancarz Kausch A, Dietz D, Bhattacharjee A. Transcriptional Regulation of the Sodium-activated Potassium Channel SLICK (KCNT2) Promoter by Nuclear Factor-ÎºB. J Biol Chem. 2015;290:18575-83 pubmed publisher
Moriwaki K, Shinzaki S, Miyoshi E. GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation. J Biol Chem. 2011;286:43123-33 pubmed publisher
Dai Y, Pei X, Rahmani M, Conrad D, Dent P, Grant S. Interruption of the NF-kappaB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells. Blood. 2004;103:2761-70 pubmed
Lin Y, Yao S, Veach R, Torgerson T, Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem. 1995;270:14255-8 pubmed

product information

Product ID :

BML-P601

Catalog Number :

BML-P601-0500

Product Name :

NF-κB SN50M cell permeable control peptide

Product Type :

Peptide

Size :

0.5 mg

list of Pubmed id :

26100633, 22027835, 14645003, 7782278

Product Description :

Inactive control peptide for the cell-permeable NF-κB inhibitory peptide SN50. Contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF), except this control peptide has Lys363 to Asn and Arg364 to Gly. In mouse endothelial LE-II cells induced with LPS, SN50M peptide had no measureable effect on NF-κB translocation at 50 µg/ml. In human monocytic THP-1 cells induced by LPS or TNFα, there was slight inhibition of nuclear transport at 100 µg/ml. Sold under license from Vanderbilt University.

Purity :

≥97% (HPLC)

Buffer :

Lyophilized. Counter Ion: Trifluoroacetate salt.

Storage :

-20°C