NF-κB SN50 cell permeable inhibitory peptide | Enzo Life Sciences BML-P600-0005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

NF-κB SN50 cell permeable inhibitory peptide

catalog :

BML-P600-0005

quantity :

0.5 mg

citations: 2

Reference
Moriwaki K, Shinzaki S, Miyoshi E. GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation. J Biol Chem. 2011;286:43123-33 pubmed publisher
Lin Y, Yao S, Veach R, Torgerson T, Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem. 1995;270:14255-8 pubmed

product information

Product ID :

BML-P600

Catalog Number :

BML-P600-0005

Product Name :

NF-κB SN50 cell permeable inhibitory peptide

Product Type :

Peptide

Size :

0.5 mg

list of Pubmed id :

22027835, 7782278

Product Description :

Sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NF-κB p50 linked to a peptide cell-permeablization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). Peptide inhibits translocation of the NF-κB active complex into the nucleus. In mouse endothelial LE-II cells induced with LPS, inhibition of NF-κB nuclear translocation was 88% at 50µg/ml (18 µM). In human monocytic THP-1 cells induced by LPS or TNFα there was 85% inhibition at 100µg/ml. Sold under license from Vanderbilt University.

Purity :

≥97% (HPLC)

Storage :

-20°C