Melatonin | Enzo Life Sciences BML-NS520-0001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Melatonin

catalog :

BML-NS520-0001

quantity :

1 g

citations: 10

Reference
Tamura E, Silva C, Markus R. Melatonin inhibits endothelial nitric oxide production in vitro. J Pineal Res. 2006;41:267-74 pubmed
Aydogan S, Yerer M, Goktas A. Melatonin and nitric oxide. J Endocrinol Invest. 2006;29:281-7 pubmed
Deng W, Tang S, Tseng H, Wu K. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. Blood. 2006;108:518-24 pubmed
Acuna Castroviejo D, Escames G, Leon J, Carazo A, Khaldy H. Mitochondrial regulation by melatonin and its metabolites. Adv Exp Med Biol. 2003;527:549-57 pubmed
Andrabi S, Sayeed I, Siemen D, Wolf G, Horn T. Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin. FASEB J. 2004;18:869-71 pubmed
Dobsak P, Siegelova J, Eicher J, Jancik J, Svacinová H, Vasku J, et al. Melatonin protects against ischemia-reperfusion injury and inhibits apoptosis in isolated working rat heart. Pathophysiology. 2003;9:179-187 pubmed
Matsubara E, Bryant Thomas T, Pacheco Quinto J, Henry T, Poeggeler B, Herbert D, et al. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem. 2003;85:1101-8 pubmed
Yoo Y, Yim S, Kim S, Jang H, Lea H, Hwang G, et al. Melatonin suppresses NO-induced apoptosis via induction of Bcl-2 expression in PGT-beta immortalized pineal cells. J Pineal Res. 2002;33:146-50 pubmed
Blanchard B, Pompon D, Ducrocq C. Nitrosation of melatonin by nitric oxide and peroxynitrite. J Pineal Res. 2000;29:184-92 pubmed
Lahiri D, Ghosh C. Interactions between melatonin, reactive oxygen species, and nitric oxide. Ann N Y Acad Sci. 1999;893:325-30 pubmed

product information

Product ID :

BML-NS520

Catalog Number :

BML-NS520-0001

Product Name :

Melatonin

Product Type :

Biochemical

Size :

1 g

list of Pubmed id :

16948788, 16682846, 16609073, 15206773, 15033929, 14567933, 12753069, 12220328, 11034116, 10672259

Product Description :

Endogenous agonist at melatonin MT1 and MT2 receptors. Displays antioxidant and antiapoptotic effects in numerous cell types as well as beneficial effects in various neurodegenerative diseases. It protects neuronal cells from amyloid beta-mediated oxidative damage and increases survival in an Alzheimer’s disease transgenic mouse model. Melatonin directly inhibits mitochondrial permeability transition pore (IC50 = 0.8M) and reduced the loss of neurons in a rat model of transient brain ischemia.

ALTnames :

N-Acetyl-5-methoxytryptamine

Purity :

≥98% (HPLC)

Storage :

-20°C