Neuron specific enolase monoclonal antibody (47) | Enzo Life Sciences BML-NA1501-0100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Neuron specific enolase monoclonal antibody (47)

catalog :

BML-NA1501-0100

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

NSE47

reactivity :

human, mouse, rat, dogs

application :

western blot, ELISA, immunohistochemistry

product information

Product ID :

BML-NA1501

Catalog Number :

BML-NA1501-0100

Product Name :

Neuron specific enolase monoclonal antibody (47)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

Clone :

NSE47

Isotype :

IgG2b

SPECIES REACTIVITY :

Mammalian

Background :

The glycolytic enzyme enolase (2-phospho-D-glycerate hydrolase) is composed of two subunits and exists in three molecular forms in human brain: non-neuronal enolase (NNE; α,α’-enolase), neuron-specific enolase (NSE; γ,γ’-enolase, also known as 14-3-2 protein and NSP) and the short-lived heterodimer α,γ’-enolase. The neuron-specific form is a highly acidic homodimeric protein of 78kDa which has been found in central and peripheral nervous elements and also in many neuroendocrine cells and derivative tumours. NSE is regarded as the best described serum marker for small cell lung cancer (SCLC). In addition, the measurement of NSE levels in both serum and cerebrospinal fluid following cerebral ischaemia and traumatic head injury provides a reliable laboratory indicator of the degree of brain cell damage and may allow early prediction of prognostic outcome.

ALTnames :

NSE, γ, γ'-enolase, Enolase 2, ENO2

Immunogen :

Neuron-specific enolase extracted from cow brain.

Specificity :

Recognizes NSE in a wide range of mammalian species.

Buffer :

Liquid. In PBS containing 0.01M sodium azide.

Uses :

Detects a band of ~76kDa by Western blot.

Application Summary :

ELISA, IHC, WB

Storage :

-20°C