This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Leukotriene C4
catalog :
BML-LC004-0050
quantity :
50 µg
citations: 8
Reference
Prié S, Guillemette G, Boulay G, Borgeat P, Sirois P. Leukotriene C4 receptors on guinea pig tracheocytes. J Pharmacol Exp Ther. 1995;275:312-8 pubmed
Hay D, Torphy T, Undem B. Cysteinyl leukotrienes in asthma: old mediators up to new tricks. Trends Pharmacol Sci. 1995;16:304-9 pubmed
Feuerstein G. Leukotrienes and the cardiovascular system. Prostaglandins. 1984;27:781-802 pubmed
Feinmark S, Cannon P. Endothelial cell leukotriene C4 synthesis results from intercellular transfer of leukotriene A4 synthesized by polymorphonuclear leukocytes. J Biol Chem. 1986;261:16466-72 pubmed
Lefer A. Leukotrienes as mediators of ischemia and shock. Biochem Pharmacol. 1986;35:123-7 pubmed
Hammarstrom S, Orning L, Bernstrom K. Metabolism of leukotrienes. Mol Cell Biochem. 1985;69:7-16 pubmed
Maclouf J, Fitzpatrick F, Murphy R. Transcellular biosynthesis of eicosanoids. Pharmacol Res. 1989;21:1-7 pubmed
Brain S, Williams T. Leukotrienes and inflammation. Pharmacol Ther. 1990;46:57-66 pubmed
product information
Product ID :
BML-LC004
Catalog Number :
BML-LC004-0050
Product Name :
Leukotriene C4
Product Type :
Biochemical
Size :
50 µg
list of Pubmed id :
8692921, 7562565, 7482995, 6431501, 3023351, 3002383, 3001504, 2657701, 2108450
Product Description :
A cysteinyl leukotriene which acts as potent agonist for contraction of smooth muscle. Induces microvascular permeability and mucus secretion in airways. Enhances growth of human airway epithelial cells. Reduces myocardial contractility and coronary blood flow. Induces long lasting hypotension. Stimulates angiogenesis. Stimulates LH8, LHRH9 and prolactin release. Produced in specific cell types or by transcellular biosynthesis and rapidly metabolized to LTD4 and LTE4. Transported by the multidrug resistance protein (MRP; Km=35nM).
ALTnames :
LTC4, 5S-Hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Purity :
≥95% (HPLC)
Storage :
-80°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.