FLUOR DE LYS®-SIRT2 deacetylase substrate | Enzo Life Sciences BML-KI179-0005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

FLUOR DE LYS®-SIRT2 deacetylase substrate

catalog :

BML-KI179-0005

quantity :

0.5 µmol

product information

Product ID :

BML-KI179

Catalog Number :

BML-KI179-0005

Product Name :

FLUOR DE LYS®-SIRT2 deacetylase substrate

Product Type :

Peptide

Size :

0.5 µmol

Product Description :

FLUOR DE LYS®-SIRT2 is a fluorogenic peptide substrate for SIRT2 (human Sirtuin 2). Based on residues 317-320 of p53 (Gln-Pro-Lys-Lys(Ac)), a site of regulatory acetylation by the PCAF acetyltransferase (lysine 320), it was the best for SIRT2 from among a panel of substrates patterned on p53, Histone H3, and Histone H4 acetylation sites. FLUOR DE LYS®-SIRT2 deacetylase substrate is deacetylated by SIRT2 at a rate of more than 50-fold that of the acetylated lysine substrate (Prod. No. BML-KI104; acetylated substrates both at 25 µM, 500 µM NAD+). Must be used in conjunction with FLUOR DE LYS® Developer II (Prod. No. BML-KI176). Sufficient for 100 assays of human recombinant SIRT2 (Prod. No. BML-SE251; 2U/well, 100 µM substrate).

Purity :

≥95% (HPLC)

Buffer :

Supplied as a 5mM solution (100 µl) in HDAC Assay Buffer.

Storage :

-80°C