Valinomycin | Enzo Life Sciences BML-KC140-0025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Valinomycin

catalog :

BML-KC140-0025

quantity :

25 mg

citations: 11

Reference
Watzlawik J, Hou X, Fricova D, Ramnarine C, Barodia S, Gendron T, et al. Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples. Autophagy. 2021;17:2613-2628 pubmed publisher
Abdalah R, Wei L, Francis K, Yu S. Valinomycin-induced apoptosis in Chinese hamster ovary cells. Neurosci Lett. 2006;405:68-73 pubmed
Ryoo I, Park H, Choo S, Hwang J, Park Y, Bae K, et al. Selective cytotoxic activity of valinomycin against HT-29 Human colon carcinoma cells via down-regulation of GRP78. Biol Pharm Bull. 2006;29:817-20 pubmed
Marques Santos L, Coqueiro V, Rumjanek V. Cyclosporin A does not protect the disruption of the inner mitochondrial membrane potential induced by potassium ionophores in intact K562 cells. Cell Biol Int. 2006;30:197-204 pubmed
Paananen A, Jarvinen K, Sareneva T, Salkinoja Salonen M, Timonen T, Hölttä E. Valinomycin-induced apoptosis of human NK cells is predominantly caspase independent. Toxicology. 2005;212:37-45 pubmed
Furlong I, Lopez Mediavilla C, Ascaso R, Lopez Rivas A, Collins M. Induction of apoptosis by valinomycin: mitochondrial permeability transition causes intracellular acidification. Cell Death Differ. 1998;5:214-21 pubmed
Inai Y, Yabuki M, Kanno T, Akiyama J, Yasuda T, Utsumi K. Valinomycin induces apoptosis of ascites hepatoma cells (AH-130) in relation to mitochondrial membrane potential. Cell Struct Funct. 1997;22:555-63 pubmed
Deckers C, Lyons A, Samuel K, Sanderson A, Maddy A. Alternative pathways of apoptosis induced by methylprednisolone and valinomycin analyzed by flow cytometry. Exp Cell Res. 1993;208:362-70 pubmed
Harada H, Morita M, Suketa Y. K+ ionophores inhibit nerve growth factor-induced neuronal differentiation in rat adrenal pheochromocytoma PC12 cells. Biochim Biophys Acta. 1994;1220:310-4 pubmed
Luvisetto S, Schemehl I, Canton M, Azzone G. The effect of respiration on the permeability of the mitochondrial membrane to ions. Biochim Biophys Acta. 1994;1186:12-8 pubmed
Orlov V, Antonenko Y, Bulychev A, Yaguzhinsky L. Combination of the electrogenic ionophores, valinomycin and CCCP, can lead to non-electrogenic K+/H+ exchange on bilayer lipid membranes. FEBS Lett. 1994;345:104-6 pubmed

product information

Product ID :

BML-KC140

Catalog Number :

BML-KC140-0025

Product Name :

Valinomycin

Product Type :

Biochemical

Size :

25 mg

list of Pubmed id :

16857314, 16595926, 16376584, 15876477, 10200467, 9431461, 8375466, 8305504, 8011661, 7515356

Product Description :

A potassium ionophore. Induces mitochondrial swelling. Induces apoptosis in CHO cells and other cell lines. Antagonizes endothelin-induced vasoconstriction (IC50=0.3µM).

Purity :

≥97% (TLC), ≥92% (HPLC)

Storage :

-20°C