This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Ellipticine
catalog :
BML-GR315-0010
quantity :
10 mg
citations: 3
Reference
Chang C, Puga A. Constitutive activation of the aromatic hydrocarbon receptor. Mol Cell Biol. 1998;18:525-35 pubmed
Froelich Ammon S, Patchan M, Osheroff N, Thompson R. Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy. J Biol Chem. 1995;270:14998-5004 pubmed
Ohashi M, Sugikawa E, Nakanishi N. Inhibition of p53 protein phosphorylation by 9-hydroxyellipticine: a possible anticancer mechanism. Jpn J Cancer Res. 1995;86:819-27 pubmed
product information
Product ID :
BML-GR315
Catalog Number :
BML-GR315-0010
Product Name :
Ellipticine
Product Type :
Biochemical
Size :
10 mg
list of Pubmed id :
9418899, 7797481, 7591958
Product Description :
A DNA-intercalating antitumor agent. Inhibits DNA topoisomerase II. Inhibits the phosphorylation of p53 in Lewis lung carcinoma cells and induces apoptosis. Inhibits cytochrome P-450-1A1.
ALTnames :
5,11-Dimethyl-6H-pyrido[4,3-b]carbazole
Purity :
≥98% (TLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.