Puromycin . 2HCl | Enzo Life Sciences BML-GR312-0250 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Puromycin . 2HCl

catalog :

BML-GR312-0250

quantity :

250 mg

citations: 10

Reference
Meister S, Storck S, Hameister E, Behl C, Weggen S, Clement A, et al. Expression of the ALS-causing variant hSOD1(G93A) leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood-spinal cord barrier model. J Cereb Blood Flow Metab. 2015;35:1112-21 pubmed publisher
Balasubramanian S, Matasci M, Kadlecova Z, Baldi L, Hacker D, Wurm F. Rapid recombinant protein production from piggyBac transposon-mediated stable CHO cell pools. J Biotechnol. 2015;200:61-9 pubmed publisher
Söderlund G, Haarhaus M, Chisalita S, Arnqvist H. Inhibition of puromycin-induced apoptosis in breast cancer cells by IGF-I occurs simultaneously with increased protein synthesis. Neoplasma. 2004;51:1-11 pubmed
Sanwal V, Pandya M, Bhaskaran M, Franki N, Reddy K, Ding G, et al. Puromycin aminonucleoside induces glomerular epithelial cell apoptosis. Exp Mol Pathol. 2001;70:54-64 pubmed
Fernandez L, Romero M, Soto H, Mosquera J. Increased apoptosis in acute puromycin aminonucleoside nephrosis. Exp Nephrol. 2001;9:99-108 pubmed
Shiiki H, Sasaki Y, Nishino T, Kimura T, Kurioka H, Fujimoto S, et al. Cell proliferation and apoptosis of the glomerular epithelial cells in rats with puromycin aminonucleoside nephrosis. Pathobiology. 1998;66:221-9 pubmed
Kaufmann S, Desnoyers S, Ottaviano Y, Davidson N, Poirier G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 1993;53:3976-85 pubmed
Chow S, Peters I, Orrenius S. Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis. Exp Cell Res. 1995;216:149-59 pubmed
Constam D, Tobler A, Rensing Ehl A, Kemler I, Hersh L, Fontana A. Puromycin-sensitive aminopeptidase. Sequence analysis, expression, and functional characterization. J Biol Chem. 1995;270:26931-9 pubmed
Davidoff A, Mendelow B. Unexpected cytokinetic effects induced by puromycin include a G2-arrest, a metaphase-mitotic-arrest, and apoptosis. Leuk Res. 1992;16:1077-85 pubmed

product information

Product ID :

BML-GR312

Catalog Number :

BML-GR312-0250

Product Name :

Puromycin . 2HCl

Product Type :

Biochemical

Size :

250 mg

list of Pubmed id :

25853911, 25758242, 15004651, 11170791, 11150858, 9732237, 8358726, 7813615, 7592939, 1434744

Product Description :

Inhibits protein synthesis. Inhibits translation by causing premature release of nascent polypeptide. Induces apoptosis.

ALTnames :

3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine . 2HCl, 3'-(α-Amino-p-methoxy-hydrocinnamamido-3'-deoxy-N,N-dimethyl-adenosine . 2HCl

Purity :

≥98% (HPLC, TLC)

Storage :

-20°C