Mitomycin C | Enzo Life Sciences BML-GR311-0010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Mitomycin C

catalog :

BML-GR311-0010

quantity :

10 mg

citations: 10

Reference
Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun. 2015;6:10068 pubmed publisher
Kishibe M, Griffin T, Radek K. Keratinocyte nicotinic acetylcholine receptor activation modulates early TLR2-mediated wound healing responses. Int Immunopharmacol. 2015;29:63-70 pubmed publisher
Bastian A, Thorpe J, Disch B, Bailey Downs L, Gangjee A, Devambatla R, et al. A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer. J Pharmacol Exp Ther. 2015;353:392-404 pubmed publisher
Gao Y, Wei J, Han J, Wang X, Su G, Zhao Y, et al. The novel function of OCT4B isoform-265 in genotoxic stress. Stem Cells. 2012;30:665-72 pubmed publisher
Mladenov E, Tsaneva I, Anachkova B. Activation of the S phase DNA damage checkpoint by mitomycin C. J Cell Physiol. 2007;211:468-76 pubmed
Sasaki M, Okamura M, Ideo A, Shimada J, Suzuki F, Ishihara M, et al. Re-evaluation of tumor-specific cytotoxicity of mitomycin C, bleomycin and peplomycin. Anticancer Res. 2006;26:3373-80 pubmed
Hata T, Hoshi T, Kanamori K, Matsumae A, Sano Y, Shima T, et al. Mitomycin, a new antibiotic from Streptomyces. I. J Antibiot (Tokyo). 1956;9:141-6 pubmed
Park I, Park M, Hwang C, Rhee C, Whang D, Jang J, et al. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner in human gastric adenocarcinoma cells. Cancer Lett. 2000;158:125-32 pubmed
Tee A, Proud C. DNA-damaging agents cause inactivation of translational regulators linked to mTOR signalling. Oncogene. 2000;19:3021-31 pubmed
Hsueh C, Chiu C, Kelsen D, Schwartz G. Selective inhibition of cyclooxygenase-2 enhances mitomycin-C-induced apoptosis. Cancer Chemother Pharmacol. 2000;45:389-96 pubmed

product information

Product ID :

BML-GR311

Catalog Number :

BML-GR311-0010

Product Name :

Mitomycin C

Product Type :

Biochemical

Size :

10 mg

list of Pubmed id :

26632666, 26071220, 25720766, 22247013, 17167777, 17094455, 13385186, 10960761, 10871854, 10803922

Product Description :

Antitumor antibiotic. DNA crosslinking and damaging agent. Inhibitor of DNA synthesis, nuclear division and cancer cells. DNA intercalating agent. Induces apoptosis in a variety of cells via a p53-dependent pathway.

Purity :

≥95% (Assay)

Storage :

-20°C