Etoposide | Enzo Life Sciences BML-GR307-0100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Etoposide

catalog :

BML-GR307-0100

quantity :

100 mg

citations: 10

Reference
Bock F, Tanzer M, Haschka M, Krumschnabel G, Sohm B, Goetsch K, et al. The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death. Sci Rep. 2015;5:11268 pubmed publisher
Liu M, Chen Y, Zhang L, Wang Q, Ma X, Li X, et al. Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II. J Biol Chem. 2015;290:14418-29 pubmed publisher
Rebsamen M, Meylan E, Curran J, Tschopp J. The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases. Cell Death Differ. 2008;15:1804-11 pubmed publisher
Baldwin E, Osheroff N. Etoposide, topoisomerase II and cancer. Curr Med Chem Anticancer Agents. 2005;5:363-72 pubmed
Meresse P, Dechaux E, Monneret C, Bertounesque E. Etoposide: discovery and medicinal chemistry. Curr Med Chem. 2004;11:2443-66 pubmed
Wang Y, Zhou R, Liliemark J, Gruber A, Lindemalm S, Albertioni F, et al. In vitro topo II--DNA complex accumulation and cytotoxicity of etoposide in leukaemic cells from patients with acute myelogenous and chronic lymphocytic leukaemia. Leuk Res. 2001;25:133-40 pubmed
Aoyama M, Grabowski D, Holmes K, Rybicki L, Bukowski R, Ganapathi M, et al. Cell cycle phase specificity in the potentiation of etoposide-induced DNA damage and apoptosis by KN-62, an inhibitor of calcium-calmodulin-dependent enzymes. Biochem Pharmacol. 2001;61:49-54 pubmed
Johnson C, Padget K, Austin C, Turner B. Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. J Biol Chem. 2001;276:4539-42 pubmed
Sawada M, Nakashima S, Banno Y, Yamakawa H, Hayashi K, Takenaka K, et al. Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells. Cell Death Differ. 2000;7:761-72 pubmed
Mascaux C, Paesmans M, Berghmans T, Branle F, Lafitte J, Lemaitre F, et al. A systematic review of the role of etoposide and cisplatin in the chemotherapy of small cell lung cancer with methodology assessment and meta-analysis. Lung Cancer. 2000;30:23-36 pubmed

product information

Product ID :

BML-GR307

Catalog Number :

BML-GR307-0100

Product Name :

Etoposide

Product Type :

Biochemical

Size :

100 mg

list of Pubmed id :

26062895, 25914138, 18756281, 16101488, 15379707, 11166828, 11137708, 11136718, 11042671, 11008007

Product Description :

Antitumor reagent. Topoisomerase II inhibitor. Induces apoptosis by FasL. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cancer cells.

ALTnames :

4-Desmethylepipodophyllotoxin 9-(4,6-O-ethylidene)-β-D-glucopyranoside, VP-16-213

Purity :

≥95% (HPLC)

Storage :

Ambient