This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Ciglitazone
catalog :
BML-GR205-0005
quantity :
5 mg
citations: 6
Reference
Clark R, Bishop Bailey D, Estrada Hernandez T, Hla T, Puddington L, Padula S. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses. J Immunol. 2000;164:1364-71 pubmed
Xin X, Yang S, Kowalski J, Gerritsen M. Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J Biol Chem. 1999;274:9116-21 pubmed
Jha R. Thiazolidinediones--the new insulin enhancers. Clin Exp Hypertens. 1999;21:157-66 pubmed
Lohrke B, Viergutz T, Shahi S, Pohland R, Wollenhaupt K, Goldammer T, et al. Detection and functional characterisation of the transcription factor peroxisome proliferator-activated receptor gamma in lutein cells. J Endocrinol. 1998;159:429-39 pubmed
Willson T, Cobb J, Cowan D, Wiethe R, Correa I, Prakash S, et al. The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones. J Med Chem. 1996;39:665-8 pubmed
Cantello B, Cawthorne M, Cottam G, Duff P, Haigh D, Hindley R, et al. [[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents. J Med Chem. 1994;37:3977-85 pubmed
product information
Product ID :
BML-GR205
Catalog Number :
BML-GR205-0005
Product Name :
Ciglitazone
Product Type :
Biochemical
Size :
5 mg
list of Pubmed id :
10640751, 10085162, 10052651, 9834460, 8576907, 7966158
Product Description :
Ciglitazone is a thiazolidinedione type of antihyperglycemic agent. It displays antihyperglycemic activity in genetically obese C57 Bl/6 ob/ob mice and is a selective PPARγ agonist (EC50=3 µM). Inhibits HUVEC differentiation and angiogenesis and also stimulates adipogenesis and decreases osteoblastogenesis in human mesenchymal stem cells.
Purity :
≥98% (HPLC)
Storage :
Ambient
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.