This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Lovastatin
catalog :
BML-G226-0010
quantity :
10 mg
citations: 6
Reference
Gioia M, Vindigni G, Testa B, Raniolo S, Fasciglione G, Coletta M, et al. Membrane Cholesterol Modulates LOX-1 Shedding in Endothelial Cells. PLoS ONE. 2015;10:e0141270 pubmed publisher
Kwak B, Mulhaupt F, Myit S, Mach F. Statins as a newly recognized type of immunomodulator. Nat Med. 2000;6:1399-402 pubmed
Hancock J, Magee A, Childs J, Marshall C. All ras proteins are polyisoprenylated but only some are palmitoylated. Cell. 1989;57:1167-77 pubmed
Mendola C, Backer J. Lovastatin blocks N-ras oncogene-induced neuronal differentiation. Cell Growth Differ. 1990;1:499-502 pubmed
Vincent T, Wulfert E, Merler E. Inhibition of growth factor signaling pathways by lovastatin. Biochem Biophys Res Commun. 1991;180:1284-9 pubmed
Jakobisiak M, Bruno S, Skierski J, Darzynkiewicz Z. Cell cycle-specific effects of lovastatin. Proc Natl Acad Sci U S A. 1991;88:3628-32 pubmed
product information
Product ID :
BML-G226
Catalog Number :
BML-G226-0010
Product Name :
Lovastatin
Product Type :
Biochemical
Size :
10 mg
list of Pubmed id :
26495844, 11100127, 2661017, 2278880, 1953779, 1673788
Product Description :
Inhibits cholesterol/isoprenoid biosynthesis by inhibition of HMG-CoA reductase (Ki for acid form is 1nM) and blocks protein isoprenylation and reduces plasma cholesterol levels in humans. Causes cells to arrest early in the G1 phase. Induces apoptosis in cancer cells.
ALTnames :
Mevinolin, 6-α-Methylcompactin
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.