Resveratrol | Enzo Life Sciences BML-FR104-0500 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Resveratrol

catalog :

BML-FR104-0500

quantity :

500 mg

citations: 10

Reference
Rius C, Abu Taha M, Hermenegildo C, Piqueras L, Cerda Nicolas J, Issekutz A, et al. Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-?B activation and peroxisome proliferator-activated receptor-gamma upregulation. J Immunol. 2010;185:3718-27 pubmed publisher
Saiko P, Szakmary A, Jaeger W, Szekeres T. Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad?. Mutat Res. 2008;658:68-94 pubmed
Sexton E, Van Themsche C, Leblanc K, Parent S, Lemoine P, Asselin E. Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells. Mol Cancer. 2006;5:45 pubmed
Borra M, Smith B, Denu J. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280:17187-95 pubmed
Kutuk O, Adli M, Poli G, Basaga H. Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts. Biofactors. 2004;20:1-10 pubmed
Martín A, Villegas I, La Casa C, de la Lastra C. Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats. Biochem Pharmacol. 2004;67:1399-410 pubmed
Howitz K, Bitterman K, Cohen H, Lamming D, Lavu S, Wood J, et al. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003;425:191-6 pubmed
Brandolini V, Maietti A, Tedeschi P, Durini E, Vertuani S, Manfredini S. Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-beta-D-glucopyranosides. J Agric Food Chem. 2002;50:7407-11 pubmed
Haworth R, Avkiran M. Inhibition of protein kinase D by resveratrol. Biochem Pharmacol. 2001;62:1647-51 pubmed
Dörrie J, Gerauer H, Wachter Y, Zunino S. Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells. Cancer Res. 2001;61:4731-9 pubmed

product information

Product ID :

BML-FR104

Catalog Number :

BML-FR104-0500

Product Name :

Resveratrol

Product Type :

Biochemical

Size :

500 mg

list of Pubmed id :

20709957, 17890139, 17044934, 15749705, 15096656, 15013856, 12939617, 12452667, 11755118, 11406544

Product Description :

Phenolic antioxidant found in grapes and wine. Potent activator of human deacetylase SIRT1 (maximum effect at 100-200μM). Increases longevity in yeast. Displays antiproliferative effect on human breast epithelial cells. Displays a variety of pharmacological activities including: estrogen receptor agonist activity, inhibition of ribonucleotide reductase and DNA synthesis, inhibition of eicosanoid synthesis, cell cycle arrest at S/G2 phase and induction of apoptosis. Inhibits PKD in vitro (IC50=200μM) and in vivo (IC50=800μM), but not PKC isoforms. Protects against 4-hydroxynonenal (4-HNE) induced oxidative stress and apoptosis. Shows cancer chemopreventive activity. Specific inhibitor of cyclooxygenase-1 (COX-1). Inhibits the hydroperoxidase activity of COX-1.

ALTnames :

trans-3,4',5-Trihydroxystilbene

Purity :

≥98% (HPLC)

Storage :

-20°C