DAPH | Enzo Life Sciences BML-EI386-0005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

DAPH

catalog :

BML-EI386-0005

quantity :

5 mg

citations: 3

Reference
Wang H, Duennwald M, Roberts B, Rozeboom L, Zhang Y, Steele A, et al. Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proc Natl Acad Sci U S A. 2008;105:7159-64 pubmed publisher
Blanchard B, Chen A, Rozeboom L, Stafford K, Weigele P, Ingram V. Efficient reversal of Alzheimer's disease fibril formation and elimination of neurotoxicity by a small molecule. Proc Natl Acad Sci U S A. 2004;101:14326-32 pubmed
Justicia C, Planas A. Transforming growth factor-alpha acting at the epidermal growth factor receptor reduces infarct volume after permanent middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab. 1999;19:128-32 pubmed

product information

Product ID :

BML-EI386

Catalog Number :

BML-EI386-0005

Product Name :

DAPH

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

18480256, 15388848, 10027766

Product Description :

DAPH abolishes or greatly reduces previously existing fully formed β-amyloid (1-42) fibrils and eliminates β-amyloid (1-42) peptide neurotoxicity. Also inhibits EGFR kinase. IC50 for inhibition of β-sheet content of aggregated β-amyloid (1-42) is 4.5µM.

ALTnames :

4,5-Dianilinophthalimide, CGP-52411

Purity :

≥98% (HPLC)

Storage :

-20°C