This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Tranylcypromine
catalog :
BML-EI217-0001
quantity :
1 g
citations: 4
Reference
Zhao X, Parpart S, Takai A, Roessler S, Budhu A, Yu Z, et al. Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM(+) AFP(+) hepatocellular carcinoma. Oncogene. 2015;34:5095-104 pubmed publisher
Palumbo Zerr K, Zerr P, Distler A, Fliehr J, Mancuso R, Huang J, et al. Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis. Nat Med. 2015;21:150-8 pubmed publisher
Lee M, Wynder C, Schmidt D, McCafferty D, Shiekhattar R. Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol. 2006;13:563-7 pubmed
Silverman R, Zieske P. Mechanism of inactivation of monoamine oxidase by 1-phenylcyclopropylamine. Biochemistry. 1985;24:2128-38 pubmed
product information
Product ID :
BML-EI217
Catalog Number :
BML-EI217-0001
Product Name :
Tranylcypromine
Product Type :
Biochemical
Size :
1 g
list of Pubmed id :
25597408, 25581517, 16793513, 3995007
Product Description :
Inhibits prostacyclin synthase. Monoamine oxidase inhibitor. Effective small molecule inhibitor of histone demethylation. Inhibits the demethylase BHC110/LSD1 (IC50<2μM). When combined with a GSK-3 inhibitor, it causes reprogramming of human primary keratinocyte transduced with Oct4 and Klf4.
ALTnames :
Trans(±)-2-phenylcyclopropanamine, SKF trans-355, 2-PCPA
Purity :
≥98% (HPLC)
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.