Tyrphostin 47 (RG-50864) (AG-213) | Enzo Life Sciences BML-EI188-0025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Tyrphostin 47 (RG-50864) (AG-213)

catalog :

BML-EI188-0025

quantity :

25 mg

citations: 5

Reference
Levitzki A, Gazit A. Tyrosine kinase inhibition: an approach to drug development. Science. 1995;267:1782-8 pubmed
Yaish P, Gazit A, Gilon C, Levitzki A. Blocking of EGF-dependent cell proliferation by EGF receptor kinase inhibitors. Science. 1988;242:933-5 pubmed
Lyall R, Zilberstein A, Gazit A, Gilon C, Levitzki A, Schlessinger J. Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation. J Biol Chem. 1989;264:14503-9 pubmed
Gazit A, Yaish P, Gilon C, Levitzki A. Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J Med Chem. 1989;32:2344-52 pubmed
Levitzki A, Gilon C. Tyrphostins as molecular tools and potential antiproliferative drugs. Trends Pharmacol Sci. 1991;12:171-4 pubmed

product information

Product ID :

BML-EI188

Catalog Number :

BML-EI188-0025

Product Name :

Tyrphostin 47 (RG-50864) (AG-213)

Product Type :

Biochemical

Size :

25 mg

list of Pubmed id :

7892601, 3263702, 2788167, 2552117, 1862529

Product Description :

A potent inhibitor of EGF receptor kinase activity (IC50‘s:EGFR = 2.4 µM, PDGFR = 3.5 µM, p210bcr-abl=5.9 µM, insulin receptor = 640 µM).

Purity :

≥99% (TLC)

Storage :

Ambient