Domoic acid | Enzo Life Sciences BML-EA117-0001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Domoic acid

catalog :

BML-EA117-0001

quantity :

1 mg

citations: 10

Reference
Scallet A, Schmued L, Johannessen J. Neurohistochemical biomarkers of the marine neurotoxicant, domoic acid. Neurotoxicol Teratol. 2005;27:745-52 pubmed
Hampson D, Manalo J. The activation of glutamate receptors by kainic acid and domoic acid. Nat Toxins. 1998;6:153-8 pubmed
Alfonso M, Duran R, Duarte C, Ferreira I, Carvalho A. Domoic acid induced release of [3H]GABA in cultured chick retina cells. Neurochem Int. 1994;24:267-74 pubmed
Nijjar M, Grimmelt B. Domoic acid inhibits adenylate cyclase activity in rat brain membranes. Mol Cell Biochem. 1994;136:105-11 pubmed
Agrawal S, Evans R. The primary afferent depolarizing action of kainate in the rat. Br J Pharmacol. 1986;87:345-55 pubmed
Hampson D, Wenthold R. A kainic acid receptor from frog brain purified using domoic acid affinity chromatography. J Biol Chem. 1988;263:2500-5 pubmed
Debonnel G, Beauchesne L, de Montigny C. Domoic acid, the alleged "mussel toxin," might produce its neurotoxic effect through kainate receptor activation: an electrophysiological study in the dorsal hippocampus. Can J Physiol Pharmacol. 1989;67:29-33 pubmed
Stewart G, Zorumski C, Price M, Olney J. Domoic acid: a dementia-inducing excitotoxic food poison with kainic acid receptor specificity. Exp Neurol. 1990;110:127-38 pubmed
Tasker R, Connell B, Strain S. Pharmacology of systemically administered domoic acid in mice. Can J Physiol Pharmacol. 1991;69:378-82 pubmed
Preston E, Hynie I. Transfer constants for blood-brain barrier permeation of the neuroexcitatory shellfish toxin, domoic acid. Can J Neurol Sci. 1991;18:39-44 pubmed

product information

Product ID :

BML-EA117

Catalog Number :

BML-EA117-0001

Product Name :

Domoic acid

Product Type :

Biochemical

Size :

1 mg

list of Pubmed id :

16203121, 10223631, 7912974, 7845363, 3513882, 2828372, 2540893, 2170163, 2059903, 2036614

Product Description :

Glutamate/kainate excitatory amino acid agonist with highest affinity for the kainate receptor of all known kainic acid analogs. Causes confusion and memory loss which resembles anterograde memory loss associated with Alzheimers disease.

ALTnames :

[2S-[2α,3β,4β(1Z,3E,5R)]]-2-Carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-3-pyrrolidineacetic acid

Purity :

≥95% (HPLC)

Storage :

-20°C