This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
Clozapine
catalog :
BML-D107-0500
quantity :
500 mg
citations: 10
Reference
Midkiff J, Borochoff Porte N, White D, Johnson D. Small molecule inhibitors of the Candida albicans budded-to-hyphal transition act through multiple signaling pathways. PLoS ONE. 2011;6:e25395 pubmed publisher
Roth B, Tandra S, Burgess L, Sibley D, Meltzer H. D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs. Psychopharmacology (Berl). 1995;120:365-8 pubmed
Kuoppamaki M, Syvalahti E, Hietala J. Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists. Eur J Pharmacol. 1993;245:179-82 pubmed
Kuoppamaki M, Palvimaki E, Syvalahti E, Hietala J. 5-HT1C receptor-mediated phosphoinositide hydrolysis in the rat choroid plexus after chronic treatment with clozapine. Eur J Pharmacol. 1994;255:91-7 pubmed
Zorn S, Jones S, Ward K, Liston D. Clozapine is a potent and selective muscarinic M4 receptor agonist. Eur J Pharmacol. 1994;269:R1-2 pubmed
Meltzer H. Role of serotonin in the action of atypical antipsychotic drugs. Clin Neurosci. 1995;3:64-75 pubmed
Rodrigues A, Jansen F, Leurs R, Timmerman H, Prell G. Interaction of clozapine with the histamine H3 receptor in rat brain. Br J Pharmacol. 1995;114:1523-4 pubmed
Arena J, Kass R. Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked. Mol Pharmacol. 1988;34:60-6 pubmed
Canton H, Verriele L, Colpaert F. Binding of typical and atypical antipsychotics to 5-HT1C and 5-HT2 sites: clozapine potently interacts with 5-HT1C sites. Eur J Pharmacol. 1990;191:93-6 pubmed
Ellenbroek B, Artz M, Cools A. The involvement of dopamine D1 and D2 receptors in the effects of the classical neuroleptic haloperidol and the atypical neuroleptic clozapine. Eur J Pharmacol. 1991;196:103-8 pubmed
product information
Product ID :
BML-D107
Catalog Number :
BML-D107-0500
Product Name :
Clozapine
Product Type :
Biochemical
Size :
500 mg
list of Pubmed id :
21966518, 8524985, 8387927, 8026557, 7895765, 7583621, 7541279, 2455861, 1982659, 1678712
Product Description :
Dopamine D4 and D2 receptor antagonist. High affinity for the cloned rat dopamine D4 receptor (Ki2A, 5HT2C, 5HT3, 5HT6 and 5HT7 receptors.
ALTnames :
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e]-[1,4]diazepine
Purity :
≥99% (Assay)
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.