This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Cytochrome P450 2D6 (human) polyclonal antibody
catalog :
BML-CR3245-0100
quantity :
100 µl
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
Product ID :
BML-CR3245
Catalog Number :
BML-CR3245-0100
Product Name :
Cytochrome P450 2D6 (human) polyclonal antibody
Host species :
Sheep
Clonality :
Polyclonal
Product Type :
Antibody
Size :
100 µl
SPECIES REACTIVITY :
Human
Background :
Human cytochrome P-450 2D6 (CYP2D6) is responsible for the metabolism of many psychotherapeutic drugs, and has been shown to act on MPTP a thermal product of synthetic heroin, which causes Parkinson's Disease (PD)-like symptoms in man. Mutation in the cyp2D6 gene has been reported to be associtated with PD. The association between Parkinson's Disease and genetic polymorphism in the human CYP2D6 gene has been reported. CYP2D6 has been found in first trimester human fetal liver, and in the placenta. Rat CYP2D1, the homolgue of human CYP2D6, has been shown to catalyse the conversion of hydrocodone to hydromorphone, and in rat liver microsomes it participates in the conversion of ethylmorphine to codeine and morphine.
ALTnames :
CYP2D6
Immunogen :
Synthetic peptide corresponding to the C-terminus of human CYP2D6.
Specificity :
Recognizes human CYP2D6.
Buffer :
Liquid. Serum containing 0.01% sodium azide.
Application Summary :
IHC, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.