This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
αB-Crystallin (human) polyclonal antibody
catalog :
BML-CA9360-0025
quantity :
25 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
Product ID :
BML-CA9360
Catalog Number :
BML-CA9360-0025
Product Name :
αB-Crystallin (human) polyclonal antibody
Host species :
Rabbit
Clonality :
Polyclonal
Product Type :
Antibody
Size :
25 µl
SPECIES REACTIVITY :
Human
Background :
The presence of the small heat shock protein αB-crystallin in ballooned neurons, characteristic of Pick’s and Creutzfeld-Jacob disease, and in Rosenthal fibers, characteristic of Alexander’s disease, suggests a role in the aggregation and remodelling of neurofilaments in neurodegenerative disease. Both mono- and poly-ubiquitinylated conjugates of αB-crystallin have been observed in Rosenthal fibers. Phosphorylated αB-crystallin interacts with FBX4, an F-box-containing protein that is a component of the ubiquitin-protein isopeptide ligase SCF (Skp1/Cul1/F-box), implicating αB-crystallin in the ubiquitin-proteasome pathway.
Immunogen :
Synthetic peptide corresponding to aa 1-10 of human αB-crystallin.
Application Summary :
IHC, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.