PTX3 (human) detection set [for ELISA application] | Enzo Life Sciences ALX-850-299-KI01 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

ELISA/assay

product name :

PTX3 (human) detection set [for ELISA application]

catalog :

ALX-850-299-KI01

quantity :

1 Set

citations: 10

Reference
Enkhmaa B, Anuurad E, Zhang W, Kim K, Berglund L. Diverging trajectory patterns of systemic versus vascular inflammation over age in healthy Caucasians and African-Americans. Atherosclerosis. 2015;239:509-515 pubmed publisher
Enkhmaa B, Anuurad E, Ozturk Z, Zhang W, Pearson T, Berglund L. Differential associations of serum amyloid A and pentraxin-3 with allele-specific lipoprotein(a) levels in African Americans and Caucasians. Transl Res. 2011;158:92-8 pubmed publisher
Anuurad E, Enkhmaa B, Gungor Z, Zhang W, Tracy R, Pearson T, et al. Age as a modulator of inflammatory cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2011;31:2151-6 pubmed publisher
Maugeri N, Rovere Querini P, Slavich M, Coppi G, Doni A, Bottazzi B, et al. Early and transient release of leukocyte pentraxin 3 during acute myocardial infarction. J Immunol. 2011;187:970-9 pubmed publisher
Barbui T, Carobbio A, Finazzi G, Vannucchi A, Barosi G, Antonioli E, et al. Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3. Haematologica. 2011;96:315-8 pubmed publisher
Dubin R, Shlipak M, Li Y, Ix J, De Boer I, Jenny N, et al. Racial differences in the association of pentraxin-3 with kidney dysfunction: the Multi-Ethnic Study of Atherosclerosis. Nephrol Dial Transplant. 2011;26:1903-8 pubmed publisher
Galbiati S, Causarano V, Pinzani P, Francesca S, Orlando C, Smid M, et al. Evaluation of a panel of circulating DNA, RNA and protein potential markers for pathologies of pregnancy. Clin Chem Lab Med. 2010;48:791-4 pubmed publisher
Germano G, Frapolli R, Simone M, Tavecchio M, Erba E, Pesce S, et al. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010;70:2235-44 pubmed publisher
Zanetti M, Bosutti A, Ferreira C, Vinci P, Biolo G, Fonda M, et al. Circulating pentraxin 3 levels are higher in metabolic syndrome with subclinical atherosclerosis: evidence for association with atherogenic lipid profile. Clin Exp Med. 2009;9:243-8 pubmed publisher
Rebelo S, Amel Kashipaz M, Radford P, Bainbridge S, Fiets R, Fang J, et al. Novel markers of inflammation identified in tumor necrosis factor receptor-associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line. Arthritis Rheum. 2009;60:269-80 pubmed publisher

product information

Product ID :

ALX-850-299

Catalog Number :

ALX-850-299-KI01

Product Name :

PTX3 (human) detection set [for ELISA application]

Product Type :

Kit

Size :

1 Set

list of Pubmed id :

25710295, 21757153, 21700927, 21677138, 21173097, 21079193, 20374043, 20215499, 19238513, 19116900

SPECIES REACTIVITY :

Human

Background :

Pentraxin 3 (PTX3), a member of the pentraxin family, is referred to as a long pentraxin and contains a unique PTX3 domain not found in C-reactive protein (CRP) or (Serum Amyloid P component) SAP. In contrast to CRP, PTX3 is produced from the major cell types involved in atherosclerotic lesions, namely vascular endothelial cells, vascular smooth muscle cells, macrophages, and nutrophils in response to inflammatory stimuli. Moreover, CRP is produced by the liver and represents a systemic response to local inflammation, whereas PTX3 is rapidly produced directly from damaged tissues and directly reflects the inflammatory state of the vasculature. PTX3 levels have been reported to be significantly elevated in acute myocardial infarction, and accordingly, statin treatment significantly decreases PTX3 levels. Due to the fact that PTX3 is able to reflect acute coronary syndrome (ACS) condition better than CRP, it is highly possible that PTX3 is a superior biomarker to predict future cardiovascular events.

ALTnames :

Pentraxin 3, TSG14, TNF stimulated Gene-14

Uses :

For the quantitative determination of PTX3 in human and bovine (weak) cell culture media, EDTA-plasma or serum (weak) samples.

Application Summary :

ELISA

Storage :

-20°C